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Scl-70 Antibody (Anti-Topoisomerase), in Bangalore

Detects antibodies against topoisomerase I, helping diagnose and predict severity of scleroderma and lung involvement.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
24 hours
TEST INCLUDED
1
customers
20K+Customers
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CertifiedLabs
rating
4.5+Rating
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ProvenAccuracy

What is a Scl-70 Antibody (Anti-Topoisomerase) Test in Bangalore ?

The Scl-70 Antibody test measures antibodies against topoisomerase I, a protein found inside cells. These antibodies form when the immune system attacks the body's own tissues. A positive result commonly points to systemic sclerosis (scleroderma), especially the diffuse type. It is linked to skin thickening and a higher chance of lung scarring (interstitial lung disease). Doctors use this test within an autoimmune or scleroderma panel. Results help support a diagnosis and guide monitoring and treatment. The test also helps predict which patients may need closer lung or skin follow-up. One result alone does not prove disease; clinicians combine it with symptoms, exams, imaging, and other lab tests.

Scl-70 Antibody (Anti-Topoisomerase) Test Preparation in Bangalore

No special preparation is required.

Scl-70 Antibody (Anti-Topoisomerase) Test Parameters in Bangalore

The Scl-70 Antibody (Anti-Topoisomerase) test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a Scl-70 Antibody (Anti-Topoisomerase) Test in Bangalore ?

Scl-70 Antibody (Anti-Topoisomerase) is usually ordered as part of a scleroderma or connective tissue autoimmune panel when patients have skin tightening, Raynaud's phenomenon, unexplained shortness of breath, or suspected organ fibrosis. It helps diagnose systemic sclerosis and predicts higher risk of lung and skin involvement. Abnormal results usually reflect autoimmune disease rather than lifestyle or medications. A family history of autoimmune disease may prompt earlier testing.

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Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What is anti-topoisomerase I anti-SCL-70 antibodies in Bangalore?plus

Anti-topoisomerase I (anti‑Scl‑70) antibodies are autoantibodies directed against the nuclear enzyme topoisomerase I. They are a relatively specific blood marker for systemic sclerosis—particularly the diffuse cutaneous subtype—and are found in roughly 20–40% of affected people. Their presence correlates with greater skin involvement, higher risk of interstitial lung disease and pulmonary fibrosis, and generally indicates a more severe disease course.

What does a positive anti-Scl-70 mean in Bangalore?plus

A positive anti‑Scl‑70 (anti–topoisomerase I) antibody suggests systemic sclerosis, particularly the diffuse cutaneous form. It’s linked to more extensive skin involvement and higher risk of interstitial lung disease or pulmonary fibrosis, implying a potentially more severe course. It’s not diagnostic alone — clinical evaluation, pulmonary function tests, high‑resolution chest CT and rheumatology follow‑up are recommended.

What is the disease with anti-topoisomerase antibodies in Bangalore?plus

Anti-topoisomerase I (anti–Scl‑70) antibodies are classically associated with systemic sclerosis (scleroderma), particularly the diffuse cutaneous form. Their presence correlates with more extensive skin involvement, increased risk of interstitial lung disease/pulmonary fibrosis, and generally indicates a more severe disease course and poorer prognosis. They support diagnosis and help with risk stratification alongside clinical findings and other autoantibodies.

Can you have Scl-70 antibodies and not have scleroderma in Bangalore?plus

Yes — Scl‑70 (anti‑topoisomerase I) is strongly associated with systemic sclerosis but can occasionally be detected without clinical scleroderma. A positive result warrants clinical correlation, repeat testing and specialist assessment because it increases the likelihood of developing systemic sclerosis or overlap autoimmune disease. Evaluation typically includes an ANA panel, organ screening (pulmonary, cardiac/renal) and regular follow‑up.

What does it mean if I have scleroderma antibodies in Bangalore?plus

Scleroderma antibodies (for example anticentromere, anti‑topoisomerase I, anti‑RNA polymerase III) mean your immune system is producing autoantibodies associated with systemic sclerosis. Their presence raises suspicion for scleroderma and helps predict disease subtype and organ risks, but isn’t diagnostic alone. A rheumatology evaluation, ongoing symptom monitoring and organ screening (skin, lungs, kidneys) guide further testing and management.

What is anti topoisomerase 1 a marker of in Bangalore?plus

Anti-topoisomerase I (anti‑Scl‑70) is an autoantibody against DNA topoisomerase I and serves as a serologic marker of systemic sclerosis. It is most strongly associated with the diffuse cutaneous subtype and correlates with more extensive skin involvement, a higher risk of interstitial lung disease/pulmonary fibrosis, and generally a more severe disease course.

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A friend who uses GetVisit regularly convinced me to try it for Scl-70 Antibody (Anti-Topoisomerase). Glad I did, the home collection meant there was no excuse to delay, and the report arrived faster than I expected.

Tariq Menon

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. Scl-70 Antibody (Anti-Topoisomerase) through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Vikram Iyer

Bangalore

starstarstarstarstar

Annual workplace health check required Scl-70 Antibody (Anti-Topoisomerase). I booked GetVisit in BTM Layout, Bengaluru and the home collection was smooth. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Saurabh Sheikh

Bangalore

starstarstarstarstar

My doctor wanted to see Scl-70 Antibody (Anti-Topoisomerase) before renewing my long-term prescription. GetVisit, booked in the evening, collected next morning, report by noon. My doctor had what he needed at my afternoon appointment.

Faisal Venkat

Bangalore

starstarstarstarstar

On a new medication for six months and my doctor wanted to monitor any effects with Scl-70 Antibody (Anti-Topoisomerase). GetVisit, home collection, same-day report. My doctor assessed the medication's safety profile at my consultation.

Jatin Nair

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking Scl-70 Antibody (Anti-Topoisomerase) for a baseline. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Girija Menon

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, Scl-70 Antibody (Anti-Topoisomerase) was one of several tests she ordered. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Nagesh Mathur

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Scl-70 Antibody (Anti-Topoisomerase). I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Ramesh Ansari

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. GetVisit's service in Jayanagar, Bengaluru was excellent, no travel, no waiting rooms. Scl-70 Antibody (Anti-Topoisomerase) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Debashis Agarwal

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including Scl-70 Antibody (Anti-Topoisomerase). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Swati Mukherjee

Bangalore

starstarstarstarstar

A friend who uses GetVisit regularly convinced me to try it for Scl-70 Antibody (Anti-Topoisomerase). Glad I did, the home collection meant there was no excuse to delay, and the report arrived faster than I expected.

Tariq Menon

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. Scl-70 Antibody (Anti-Topoisomerase) through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Vikram Iyer

Bangalore

starstarstarstarstar

Annual workplace health check required Scl-70 Antibody (Anti-Topoisomerase). I booked GetVisit in BTM Layout, Bengaluru and the home collection was smooth. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Saurabh Sheikh

Bangalore

starstarstarstarstar

My doctor wanted to see Scl-70 Antibody (Anti-Topoisomerase) before renewing my long-term prescription. GetVisit, booked in the evening, collected next morning, report by noon. My doctor had what he needed at my afternoon appointment.

Faisal Venkat

Bangalore

starstarstarstarstar

On a new medication for six months and my doctor wanted to monitor any effects with Scl-70 Antibody (Anti-Topoisomerase). GetVisit, home collection, same-day report. My doctor assessed the medication's safety profile at my consultation.

Jatin Nair

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking Scl-70 Antibody (Anti-Topoisomerase) for a baseline. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Girija Menon

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, Scl-70 Antibody (Anti-Topoisomerase) was one of several tests she ordered. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Nagesh Mathur

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Scl-70 Antibody (Anti-Topoisomerase). I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Ramesh Ansari

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. GetVisit's service in Jayanagar, Bengaluru was excellent, no travel, no waiting rooms. Scl-70 Antibody (Anti-Topoisomerase) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Debashis Agarwal

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including Scl-70 Antibody (Anti-Topoisomerase). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Swati Mukherjee

Bangalore

starstarstarstarstar

A friend who uses GetVisit regularly convinced me to try it for Scl-70 Antibody (Anti-Topoisomerase). Glad I did, the home collection meant there was no excuse to delay, and the report arrived faster than I expected.

Tariq Menon

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. Scl-70 Antibody (Anti-Topoisomerase) through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Vikram Iyer

Bangalore

starstarstarstarstar

Annual workplace health check required Scl-70 Antibody (Anti-Topoisomerase). I booked GetVisit in BTM Layout, Bengaluru and the home collection was smooth. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Saurabh Sheikh

Bangalore

starstarstarstarstar

My doctor wanted to see Scl-70 Antibody (Anti-Topoisomerase) before renewing my long-term prescription. GetVisit, booked in the evening, collected next morning, report by noon. My doctor had what he needed at my afternoon appointment.

Faisal Venkat

Bangalore

starstarstarstarstar

On a new medication for six months and my doctor wanted to monitor any effects with Scl-70 Antibody (Anti-Topoisomerase). GetVisit, home collection, same-day report. My doctor assessed the medication's safety profile at my consultation.

Jatin Nair

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking Scl-70 Antibody (Anti-Topoisomerase) for a baseline. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Girija Menon

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, Scl-70 Antibody (Anti-Topoisomerase) was one of several tests she ordered. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Nagesh Mathur

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Scl-70 Antibody (Anti-Topoisomerase). I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Ramesh Ansari

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. GetVisit's service in Jayanagar, Bengaluru was excellent, no travel, no waiting rooms. Scl-70 Antibody (Anti-Topoisomerase) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Debashis Agarwal

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including Scl-70 Antibody (Anti-Topoisomerase). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Swati Mukherjee

Bangalore

starstarstarstarstar

A friend who uses GetVisit regularly convinced me to try it for Scl-70 Antibody (Anti-Topoisomerase). Glad I did, the home collection meant there was no excuse to delay, and the report arrived faster than I expected.

Tariq Menon

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. Scl-70 Antibody (Anti-Topoisomerase) through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Vikram Iyer

Bangalore

starstarstarstarstar

Annual workplace health check required Scl-70 Antibody (Anti-Topoisomerase). I booked GetVisit in BTM Layout, Bengaluru and the home collection was smooth. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Saurabh Sheikh

Bangalore

starstarstarstarstar

My doctor wanted to see Scl-70 Antibody (Anti-Topoisomerase) before renewing my long-term prescription. GetVisit, booked in the evening, collected next morning, report by noon. My doctor had what he needed at my afternoon appointment.

Faisal Venkat

Bangalore

starstarstarstarstar

On a new medication for six months and my doctor wanted to monitor any effects with Scl-70 Antibody (Anti-Topoisomerase). GetVisit, home collection, same-day report. My doctor assessed the medication's safety profile at my consultation.

Jatin Nair

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking Scl-70 Antibody (Anti-Topoisomerase) for a baseline. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Girija Menon

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, Scl-70 Antibody (Anti-Topoisomerase) was one of several tests she ordered. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Nagesh Mathur

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Scl-70 Antibody (Anti-Topoisomerase). I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Ramesh Ansari

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. GetVisit's service in Jayanagar, Bengaluru was excellent, no travel, no waiting rooms. Scl-70 Antibody (Anti-Topoisomerase) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Debashis Agarwal

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including Scl-70 Antibody (Anti-Topoisomerase). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Swati Mukherjee

Bangalore