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NPM1 (NUCLEOPHOSMIN1) GENE - AML

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NPM1 (NUCLEOPHOSMIN1) GENE - AML
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NPM1 (NUCLEOPHOSMIN1) GENE - AML, in Bangalore

Detects mutations in the NPM1 gene linked to acute myeloid leukemia; guides diagnosis, prognosis, and monitoring.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
24 hours
TEST INCLUDED
1
customers
20K+Customers
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CertifiedLabs
rating
4.5+Rating
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ProvenAccuracy

What is a NPM1 (NUCLEOPHOSMIN1) GENE - AML Test in Bangalore ?

This test looks for changes (mutations) in the NPM1 gene that are linked to acute myeloid leukemia (AML). NPM1 helps control how cells grow and where certain proteins sit inside the cell. Finding an NPM1 mutation helps confirm a diagnosis of AML. It also gives doctors information about likely disease behavior and treatment options. After treatment, the test can monitor remaining cancer cells and detect early relapse.

NPM1 (NUCLEOPHOSMIN1) GENE - AML Test Preparation in Bangalore

No special preparation is required.

NPM1 (NUCLEOPHOSMIN1) GENE - AML Test Parameters in Bangalore

The NPM1 (NUCLEOPHOSMIN1) GENE - AML test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a NPM1 (NUCLEOPHOSMIN1) GENE - AML Test in Bangalore ?

NPM1 (NUCLEOPHOSMIN1) GENE - AML is commonly included in AML molecular panels used when blood counts or bone marrow tests suggest leukemia. Doctors order it for symptoms like fatigue, easy bruising, frequent infections, or abnormal blood tests. It helps diagnose and classify AML, guide treatment choices, and monitor response or relapse. Abnormal results are caused by somatic mutations in leukemia cells; a family history of blood cancers may make testing more likely.

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Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What is the NPM1 gene mutation in AML in Bangalore?plus

The NPM1 mutation in acute myeloid leukemia (AML) is a common genetic change that causes nucleophosmin to relocate from the nucleus to the cytoplasm, disrupting normal cell regulation. It appears in roughly 25–35% of adult AML cases and, when not accompanied by high-risk mutations, is associated with better chemotherapy response. Molecular testing identifies it for prognosis, risk stratification, and treatment planning.

What is the survival rate for NPM1 AML in Bangalore?plus

NPM1‑mutated AML generally has a better prognosis than other AML subtypes. With modern therapy, complete remission rates are high and 5‑year overall survival is roughly 40–60% overall. Survival is higher (often >50–60%) in younger patients and those without a co‑occurring FLT3‑ITD mutation, and substantially lower in older patients or with adverse additional mutations.

What is the most common gene mutation in AML in Bangalore?plus

The most common gene mutation in acute myeloid leukemia (AML) is NPM1 mutation. It occurs in about 25–30% of adult AML cases and is particularly frequent in patients with a normal karyotype. NPM1 mutations often coexist with FLT3 mutations (especially FLT3‑ITD), which can affect prognosis. Detection guides risk stratification and targeted therapy selection.

Which gene is responsible for AML in Bangalore?plus

Acute myeloid leukemia (AML) is not caused by a single gene but by various acquired (somatic) mutations that disrupt blood-cell development. Commonly implicated genes include FLT3 and NPM1, with frequent involvement of DNMT3A, IDH1/2, RUNX1, CEBPA, TP53, ASXL1, and KIT. The specific mutated driver varies by patient and influences prognosis and treatment choices.

Is AML 100% curable in Bangalore?plus

Acute myeloid leukemia (AML) is not 100% curable. Some patients—especially younger people with favorable genetic features who achieve complete remission and sometimes receive stem cell transplant—can attain long-term remission or cure. Prognosis varies by age, genetic mutations, disease subtype, and treatment response. Relapse is possible, so ongoing monitoring and individualized therapy are important.

Is NPM1 a favorable risk factor in Bangalore?plus

Yes — NPM1 mutation is generally considered a favorable prognostic marker in acute myeloid leukemia, particularly with a normal karyotype and absent or low‑allelic‑ratio FLT3‑ITD. It associates with higher remission rates and improved overall survival, influences risk stratification and treatment choices, and can be used for measurable residual disease monitoring. Impact varies with co‑occurring mutations and clinical context.

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My doctor ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Murali Bajaj

Bangalore

starstarstarstarstar

Pre-conception genetic screening included NPM1 (NUCLEOPHOSMIN1) GENE - AML on our genetic counsellor's advice. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Falguni More

Bangalore

starstarstarstarstar

Prenatal genetic screening included NPM1 (NUCLEOPHOSMIN1) GENE - AML on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Sandeep Deshpande

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended NPM1 (NUCLEOPHOSMIN1) GENE - AML for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Aditya Krishnan

Bangalore

starstarstarstarstar

My doctor included NPM1 (NUCLEOPHOSMIN1) GENE - AML as part of an investigation into recurrent health issues with a possible hereditary component. I've been using GetVisit in Koramangala, Bengaluru and would highly recommend it to anyone. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Ravi Kumar

Bangalore

starstarstarstarstar

My doctor ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML as part of a genetic investigation. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Rajan Bhavsar

Bangalore

starstarstarstarstar

My haematologist ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML to determine the most appropriate treatment protocol. The phlebotomist from GetVisit visited me in Bengaluru, on time and professional. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Ketan Tiwari

Bangalore

starstarstarstarstar

My oncologist ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML for precision medicine planning. The GetVisit team in JP Nagar, Bengaluru was professional and punctual. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Lakshmi Menon

Bangalore

starstarstarstarstar

Comprehensive annual health panel, NPM1 (NUCLEOPHOSMIN1) GENE - AML was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Manoj Thakur

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking NPM1 (NUCLEOPHOSMIN1) GENE - AML for a baseline. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Ramakant Pillai

Bangalore

starstarstarstarstar

My doctor ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Murali Bajaj

Bangalore

starstarstarstarstar

Pre-conception genetic screening included NPM1 (NUCLEOPHOSMIN1) GENE - AML on our genetic counsellor's advice. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Falguni More

Bangalore

starstarstarstarstar

Prenatal genetic screening included NPM1 (NUCLEOPHOSMIN1) GENE - AML on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Sandeep Deshpande

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended NPM1 (NUCLEOPHOSMIN1) GENE - AML for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Aditya Krishnan

Bangalore

starstarstarstarstar

My doctor included NPM1 (NUCLEOPHOSMIN1) GENE - AML as part of an investigation into recurrent health issues with a possible hereditary component. I've been using GetVisit in Koramangala, Bengaluru and would highly recommend it to anyone. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Ravi Kumar

Bangalore

starstarstarstarstar

My doctor ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML as part of a genetic investigation. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Rajan Bhavsar

Bangalore

starstarstarstarstar

My haematologist ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML to determine the most appropriate treatment protocol. The phlebotomist from GetVisit visited me in Bengaluru, on time and professional. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Ketan Tiwari

Bangalore

starstarstarstarstar

My oncologist ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML for precision medicine planning. The GetVisit team in JP Nagar, Bengaluru was professional and punctual. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Lakshmi Menon

Bangalore

starstarstarstarstar

Comprehensive annual health panel, NPM1 (NUCLEOPHOSMIN1) GENE - AML was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Manoj Thakur

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking NPM1 (NUCLEOPHOSMIN1) GENE - AML for a baseline. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Ramakant Pillai

Bangalore

starstarstarstarstar

My doctor ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Murali Bajaj

Bangalore

starstarstarstarstar

Pre-conception genetic screening included NPM1 (NUCLEOPHOSMIN1) GENE - AML on our genetic counsellor's advice. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Falguni More

Bangalore

starstarstarstarstar

Prenatal genetic screening included NPM1 (NUCLEOPHOSMIN1) GENE - AML on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Sandeep Deshpande

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended NPM1 (NUCLEOPHOSMIN1) GENE - AML for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Aditya Krishnan

Bangalore

starstarstarstarstar

My doctor included NPM1 (NUCLEOPHOSMIN1) GENE - AML as part of an investigation into recurrent health issues with a possible hereditary component. I've been using GetVisit in Koramangala, Bengaluru and would highly recommend it to anyone. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Ravi Kumar

Bangalore

starstarstarstarstar

My doctor ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML as part of a genetic investigation. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Rajan Bhavsar

Bangalore

starstarstarstarstar

My haematologist ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML to determine the most appropriate treatment protocol. The phlebotomist from GetVisit visited me in Bengaluru, on time and professional. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Ketan Tiwari

Bangalore

starstarstarstarstar

My oncologist ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML for precision medicine planning. The GetVisit team in JP Nagar, Bengaluru was professional and punctual. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Lakshmi Menon

Bangalore

starstarstarstarstar

Comprehensive annual health panel, NPM1 (NUCLEOPHOSMIN1) GENE - AML was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Manoj Thakur

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking NPM1 (NUCLEOPHOSMIN1) GENE - AML for a baseline. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Ramakant Pillai

Bangalore

starstarstarstarstar

My doctor ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Murali Bajaj

Bangalore

starstarstarstarstar

Pre-conception genetic screening included NPM1 (NUCLEOPHOSMIN1) GENE - AML on our genetic counsellor's advice. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Falguni More

Bangalore

starstarstarstarstar

Prenatal genetic screening included NPM1 (NUCLEOPHOSMIN1) GENE - AML on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Sandeep Deshpande

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended NPM1 (NUCLEOPHOSMIN1) GENE - AML for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Aditya Krishnan

Bangalore

starstarstarstarstar

My doctor included NPM1 (NUCLEOPHOSMIN1) GENE - AML as part of an investigation into recurrent health issues with a possible hereditary component. I've been using GetVisit in Koramangala, Bengaluru and would highly recommend it to anyone. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Ravi Kumar

Bangalore

starstarstarstarstar

My doctor ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML as part of a genetic investigation. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Rajan Bhavsar

Bangalore

starstarstarstarstar

My haematologist ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML to determine the most appropriate treatment protocol. The phlebotomist from GetVisit visited me in Bengaluru, on time and professional. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Ketan Tiwari

Bangalore

starstarstarstarstar

My oncologist ordered NPM1 (NUCLEOPHOSMIN1) GENE - AML for precision medicine planning. The GetVisit team in JP Nagar, Bengaluru was professional and punctual. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Lakshmi Menon

Bangalore

starstarstarstarstar

Comprehensive annual health panel, NPM1 (NUCLEOPHOSMIN1) GENE - AML was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Manoj Thakur

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking NPM1 (NUCLEOPHOSMIN1) GENE - AML for a baseline. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Ramakant Pillai

Bangalore