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HLA C06

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HLA C06

Detects the HLA‑C*06 gene variant linked to higher risk of psoriasis and possible treatment response.

Home Sample collection

Centre Visit

SAMPLE TYPE

Blood

FASTING REQUIRED

GENDER

Male/Female

GET REPORTS IN

48 hours

TEST INCLUDED

20K+Customers

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What is a HLA C06 Test?

The HLA C06 test looks for a specific variant in the HLA‑C gene. This gene helps the immune system show bits of protein to immune cells. The HLA‑C*06 variant is linked to a higher chance of developing plaque psoriasis. It can also relate to age of onset, disease pattern, and responses to some treatments. Doctors use the result with clinical signs and family history. It can help confirm risk, guide treatment choices, and inform genetic counseling for families.

HLA C06 Test Preparation

No special preparation is required.

HLA C06 Test Parameters

The HLA C06 test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

Single test

Why Take a HLA C06 Test?

HLA C06 is used as part of genetic or autoimmune testing panels when psoriasis or related conditions are suspected. Doctors may order it for people with early or severe scaly skin rashes, a strong family history of psoriasis, or to help predict treatment response. The test helps identify genetic susceptibility rather than current disease activity. A positive result reflects inherited genes, not lifestyle, illness, or medication effects, and can guide care and family discussions.

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Frequently asked questions

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What is HLA Cw6 associated with?

HLA‑Cw6 is a genetic marker strongly associated with psoriasis, particularly early‑onset (type I) and guttate forms. It’s linked to family history and streptococcal‑triggered flares, tends to associate with specific clinical patterns (scalp and widespread lesions) and earlier onset, and can affect disease course. Presence of HLA‑Cw6 may also influence prognosis and response to some therapies.

What is the HLA marker for Behcet's disease?

The major HLA marker associated with Behçet’s disease is HLA‑B51 (part of the HLA‑B5 serotype). HLA‑B51 increases susceptibility, especially in Mediterranean, Middle Eastern and East Asian populations, but it is not diagnostic alone. Many affected individuals do not carry the marker, and many carriers never develop disease; clinical evaluation and other tests are required.

Which HLA is associated with psoriatic arthritis?

HLA-B27 is the HLA allele most commonly associated with psoriatic arthritis, particularly with axial involvement and sacroiliitis. Its presence increases the likelihood of spinal and joint inflammation and can influence disease pattern and prognosis. Other HLA class I alleles (for example HLA-B38 and B39) may also be implicated, but HLA-B27 is the principal genetic marker linked to psoriatic arthritis.

Which HLA is associated with lupus?

Systemic lupus erythematosus is most strongly associated with HLA class II alleles, particularly HLA-DR2 and HLA-DR3 (notably DRB1*15:01 and DRB1*03:01). These alleles correlate with higher susceptibility and autoantibody production, though associations vary by ethnicity and presence of these HLAs does not guarantee disease—genetic and environmental factors together determine risk. Testing may inform risk assessment in select cases.

What autoimmune disease is HLA related to?

Human leukocyte antigen (HLA) genes are linked to multiple autoimmune conditions. The clearest example is HLA-B27, which is strongly associated with ankylosing spondylitis and related spondyloarthropathies. Other HLA types (e.g., HLA-DR3, DR4) increase risk for diseases such as type 1 diabetes and rheumatoid arthritis. HLA testing can support diagnosis but is not definitive on its own.

What diseases are associated with HLA-C?

HLA‑C alleles are linked most strongly to psoriasis (notably HLA‑C*06:02) and psoriatic arthritis. HLA‑C variation influences viral control in HIV infection. HLA‑C matching affects transplant outcomes and graft‑versus‑host disease risk. Certain HLA‑C types have been associated with spondyloarthropathies and other inflammatory conditions, though associations are allele‑specific and vary between populations.

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Vijay Bisht was friendly, helpful, and made our home test process seamless. Grateful for his timely support and follow-up.

Usha Parvathy

Partner at Deloitte

A big thank you to Shikhar from the Visit app for going above and beyond to arrange a last-minute appointment during an urgent situation. His seamless coordination truly made a difference.

Tejas Baxix

Associate Vice President

A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

Sadaanand Asai

Employee

“The service was excellent—she was helpful, efficient, and made my recovery smooth and stress-free. Her support made a real difference.”

Ishan Kaul

Manager Administration

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