Estradiol (E2) - Book Online

Q: What happens if E2 is high?

High estradiol (E2) can cause menstrual irregularities, heavy bleeding, breast tenderness, bloating, mood swings, and fertility problems in women; in men, it may cause gynecomastia, low libido, erectile dysfunction, and reduced sperm production. Chronically high E2 raises risks of blood clots, stroke, endometrial hyperplasia/cancer, and liver issues. Evaluation by a clinician is recommended.

Q: What is a good E2 level to get pregnant?

A good estradiol (E2) for getting pregnant is a rising level that reaches roughly 200–600 pg/mL (≈730–2,200 pmol/L) before ovulation, which suggests adequate follicle maturity and boosts conception chances. Lower E2 may indicate poor follicular growth; very high E2 can signal multiple follicles or OHSS risk. Targets vary by lab, treatment and individual—discuss your results with your fertility clinician.

Q: What happens if E2 is low?

Low estradiol (E2) commonly causes menstrual irregularities or absent periods, hot flashes, night sweats, vaginal dryness, painful intercourse, low libido, mood swings, fatigue and difficulty concentrating. Long-term deficiency accelerates bone loss, raising osteoporosis and fracture risk, and can unfavorably affect cholesterol and cardiovascular health. It also impairs fertility and may require evaluation and treatment to address symptoms and prevent complications.

Q: Which hormone is called the beauty hormone?

Estrogen is often called the “beauty hormone.” Produced mainly by the ovaries, it helps preserve skin thickness, elasticity and hydration by supporting collagen production and healthy blood flow. Estrogen also influences hair growth, nail strength and fat distribution; levels decline with age and after menopause, contributing to thinner, drier skin and hair changes.

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Estradiol (E2)

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Estradiol (E2)

Measures blood estradiol, a key estrogen, to check reproductive, bone, and hormonal health.

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Centre Visit

SAMPLE TYPE

Blood

FASTING REQUIRED

GENDER

Male/Female

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25 hours

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What is a Estradiol (E2) Test?

Estradiol is a blood test that measures one form of the hormone estrogen. It plays a central role in reproductive health, bone strength, and mood regulation. Doctors use estradiol levels to assess menstrual problems, infertility, menopause status, and the effects of hormone therapy. It can also help detect ovarian or hormone-secreting tumors and pituitary issues. Levels naturally change across the menstrual cycle and with age. Results are interpreted with other hormone tests and clinical information. Your doctor may time the sample to a specific day of the cycle or repeat testing to track changes or treatment response.

Estradiol (E2) Test Preparation

No special preparation is required.

Estradiol (E2) Test Parameters

The Estradiol (E2) test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

Single test

Why Take a Estradiol (E2) Test?

Estradiol (E2) is often included in fertility or hormone panels and is ordered for irregular periods, infertility, hot flashes, or suspected ovarian problems. It helps diagnose menopause, polycystic ovary syndrome, ovarian failure, and estrogen-secreting tumors. Levels can be altered by weight changes, stress, certain drugs, or hormone therapy. A family history of early menopause or hormone-related cancers may make testing more important.

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What does estradiol E2 do?

Estradiol (E2) is the main estrogen in reproductive-age people, regulating the menstrual cycle and promoting follicle maturation and ovulation. It drives female secondary sexual characteristics (breast development), maintains bone density, influences lipid metabolism and cardiovascular health, supports vaginal and urogenital tissues and lubrication, and affects mood and cognitive function. In both sexes it helps bone maintenance and hormonal balance.

What is a normal E2 level for a woman?

Normal estradiol (E2) levels vary with menstrual phase. Typical ranges: follicular 20–150 pg/mL, mid‑cycle (ovulatory) peak 150–750 pg/mL, luteal 30–450 pg/mL. Postmenopausal values are much lower, usually <20–30 pg/mL. Exact reference ranges depend on the laboratory and assay; discuss your results with a clinician.

What happens if E2 is high?

High estradiol (E2) can cause menstrual irregularities, heavy bleeding, breast tenderness, bloating, mood swings, and fertility problems in women; in men, it may cause gynecomastia, low libido, erectile dysfunction, and reduced sperm production. Chronically high E2 raises risks of blood clots, stroke, endometrial hyperplasia/cancer, and liver issues. Evaluation by a clinician is recommended.

What is a good E2 level to get pregnant?

A good estradiol (E2) for getting pregnant is a rising level that reaches roughly 200–600 pg/mL (≈730–2,200 pmol/L) before ovulation, which suggests adequate follicle maturity and boosts conception chances. Lower E2 may indicate poor follicular growth; very high E2 can signal multiple follicles or OHSS risk. Targets vary by lab, treatment and individual—discuss your results with your fertility clinician.

What happens if E2 is low?

Low estradiol (E2) commonly causes menstrual irregularities or absent periods, hot flashes, night sweats, vaginal dryness, painful intercourse, low libido, mood swings, fatigue and difficulty concentrating. Long-term deficiency accelerates bone loss, raising osteoporosis and fracture risk, and can unfavorably affect cholesterol and cardiovascular health. It also impairs fertility and may require evaluation and treatment to address symptoms and prevent complications.

Which hormone is called the beauty hormone?

Estrogen is often called the “beauty hormone.” Produced mainly by the ovaries, it helps preserve skin thickness, elasticity and hydration by supporting collagen production and healthy blood flow. Estrogen also influences hair growth, nail strength and fat distribution; levels decline with age and after menopause, contributing to thinner, drier skin and hair changes.

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Usha Parvathy

Partner at Deloitte

A big thank you to Shikhar from the Visit app for going above and beyond to arrange a last-minute appointment during an urgent situation. His seamless coordination truly made a difference.

Tejas Baxix

Associate Vice President

A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

Sadaanand Asai

Employee

“The service was excellent—she was helpful, efficient, and made my recovery smooth and stress-free. Her support made a real difference.”

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Manager Administration

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