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EGFR Mutation Study (10 Common Mutations)

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EGFR Mutation Study (10 Common Mutations)
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EGFR Mutation Study (10 Common Mutations), in Bangalore

Detects ten common EGFR gene mutations to guide targeted treatment choices and prognosis for lung cancer.

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Tissue
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26 hours
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20K+Customers
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What is a EGFR Mutation Study (10 Common Mutations) Test in Bangalore ?

This test looks for ten common changes (mutations) in the EGFR gene. EGFR helps control how cells grow and divide. Certain mutations can make cells grow uncontrollably and drive cancers, especially non-small cell lung cancer. Finding these mutations is important because specific medicines can target them. Doctors use results to choose targeted treatments, predict likely response, and watch for resistance during therapy. Results can affect treatment plans and help avoid ineffective medicines. Sometimes the test is done on a tissue biopsy from a tumor. Results are combined with other clinical information before making treatment decisions.

EGFR Mutation Study (10 Common Mutations) Test Preparation in Bangalore

No special preparation is required.

EGFR Mutation Study (10 Common Mutations) Test Parameters in Bangalore

The EGFR Mutation Study (10 Common Mutations) test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Exon 19 deletions; L858R (Exon 21); T790M (Exon 20); G719A/C/S (Exon 18); S768I; L861Q; Exon 20 insertions; E709X; other Exon 18/21 point mutations; common activating/resistance EGFR variants

Why Take a EGFR Mutation Study (10 Common Mutations) Test in Bangalore ?

EGFR Mutation Study (10 Common Mutations) is part of molecular panels used for suspected or confirmed non-small cell lung cancer. Doctors may order it when imaging or symptoms suggest lung cancer or when a biopsy is available. It helps diagnose and guide targeted therapy, monitor treatment response, and detect resistance. Abnormal results usually reflect acquired or inherited changes in the tumor’s DNA rather than lifestyle. A strong family history of cancer or unusual clinical features may prompt testing.

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Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What are the common mutations in EGFR in Bangalore?plus

Common EGFR mutations include exon 19 deletions and the exon 21 L858R point mutation (both sensitizing to EGFR inhibitors). Other frequent alterations are exon 20 insertions and the T790M resistance mutation (exon 20). Less common activating variants include G719X (exon 18), S768I (exon 20), and L861Q (exon 21). These mutations guide targeted therapy choices.

What is the most common EGFR resistance mutation in Bangalore?plus

The most common EGFR resistance mutation is T790M — a threonine-to-methionine substitution at amino acid 790. It arises in roughly 50–60% of patients with acquired resistance to first- and second‑generation EGFR tyrosine kinase inhibitors, increases ATP affinity at the kinase “gatekeeper” residue, and reduces drug binding. Detection guides use of third‑generation inhibitors effective against T790M.

What is the EGFR mutation test in Bangalore?plus

The EGFR mutation test detects changes in the EGFR gene in cancer cells, usually from a tumor biopsy or a blood (liquid biopsy) sample. It identifies mutations (for example exon 19 deletions, L858R, T790M) that predict response or resistance to EGFR-targeted therapies, helping oncologists choose appropriate tyrosine kinase inhibitors and guide prognosis and treatment planning.

What are EGFR exon 20 insertion mutations in Bangalore?plus

EGFR exon 20 insertion mutations are in-frame insertions within exon 20 of the epidermal growth factor receptor gene that alter the kinase domain’s shape, producing constitutive receptor activation. They occur in a subset of non-small cell lung cancers and are generally less sensitive to first- and second-generation EGFR tyrosine kinase inhibitors, often requiring newer targeted agents developed specifically for this mutation class.

What are classical EGFR mutations in Bangalore?plus

Classical EGFR mutations are the common activating alterations in non–small cell lung cancer, chiefly exon 19 deletions and the exon 21 L858R point mutation. These alterations increase EGFR kinase activity and typically confer sensitivity to EGFR tyrosine kinase inhibitors. They are most frequent in adenocarcinomas, especially among non‑smokers, females, and East Asian patients; other uncommon variants can affect treatment response.

What is HER2 mutation in Bangalore?plus

HER2 mutation refers to changes in the ERBB2 gene that lead to overproduction or abnormal activity of the HER2 receptor, a cell-surface tyrosine kinase. This drives rapid cell growth and is implicated especially in certain breast and gastric cancers. HER2 alterations affect prognosis and guide use of targeted therapies (for example, trastuzumab, pertuzumab, tyrosine kinase inhibitors) to block HER2-driven signaling.

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My haematologist ordered EGFR Mutation Study (10 Common Mutations) to determine the most appropriate treatment protocol. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Paresh Mishra

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended EGFR Mutation Study (10 Common Mutations) for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Nalini Venkat

Bangalore

starstarstarstarstar

Prenatal genetic screening included EGFR Mutation Study (10 Common Mutations) on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Janki Tripathi

Bangalore

starstarstarstarstar

Pre-conception genetic screening included EGFR Mutation Study (10 Common Mutations) on our genetic counsellor's advice. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Durga Jain

Bangalore

starstarstarstarstar

My doctor ordered EGFR Mutation Study (10 Common Mutations) as part of a genetic investigation. I booked GetVisit in Yelahanka, Bengaluru and the home collection was smooth. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Yuvraj Shetty

Bangalore

starstarstarstarstar

My doctor included EGFR Mutation Study (10 Common Mutations) as part of an investigation into recurrent health issues with a possible hereditary component. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Ajay Contractor

Bangalore

starstarstarstarstar

My doctor ordered EGFR Mutation Study (10 Common Mutations) after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Venkatesan Rajan

Bangalore

starstarstarstarstar

My oncologist ordered EGFR Mutation Study (10 Common Mutations) for precision medicine planning. I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Lalit Swamy

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included EGFR Mutation Study (10 Common Mutations). My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Debashis Agarwal

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including EGFR Mutation Study (10 Common Mutations). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Sourav Pathak

Bangalore

starstarstarstarstar

My haematologist ordered EGFR Mutation Study (10 Common Mutations) to determine the most appropriate treatment protocol. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Paresh Mishra

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended EGFR Mutation Study (10 Common Mutations) for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Nalini Venkat

Bangalore

starstarstarstarstar

Prenatal genetic screening included EGFR Mutation Study (10 Common Mutations) on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Janki Tripathi

Bangalore

starstarstarstarstar

Pre-conception genetic screening included EGFR Mutation Study (10 Common Mutations) on our genetic counsellor's advice. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Durga Jain

Bangalore

starstarstarstarstar

My doctor ordered EGFR Mutation Study (10 Common Mutations) as part of a genetic investigation. I booked GetVisit in Yelahanka, Bengaluru and the home collection was smooth. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Yuvraj Shetty

Bangalore

starstarstarstarstar

My doctor included EGFR Mutation Study (10 Common Mutations) as part of an investigation into recurrent health issues with a possible hereditary component. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Ajay Contractor

Bangalore

starstarstarstarstar

My doctor ordered EGFR Mutation Study (10 Common Mutations) after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Venkatesan Rajan

Bangalore

starstarstarstarstar

My oncologist ordered EGFR Mutation Study (10 Common Mutations) for precision medicine planning. I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Lalit Swamy

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included EGFR Mutation Study (10 Common Mutations). My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Debashis Agarwal

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including EGFR Mutation Study (10 Common Mutations). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Sourav Pathak

Bangalore

starstarstarstarstar

My haematologist ordered EGFR Mutation Study (10 Common Mutations) to determine the most appropriate treatment protocol. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Paresh Mishra

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended EGFR Mutation Study (10 Common Mutations) for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Nalini Venkat

Bangalore

starstarstarstarstar

Prenatal genetic screening included EGFR Mutation Study (10 Common Mutations) on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Janki Tripathi

Bangalore

starstarstarstarstar

Pre-conception genetic screening included EGFR Mutation Study (10 Common Mutations) on our genetic counsellor's advice. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Durga Jain

Bangalore

starstarstarstarstar

My doctor ordered EGFR Mutation Study (10 Common Mutations) as part of a genetic investigation. I booked GetVisit in Yelahanka, Bengaluru and the home collection was smooth. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Yuvraj Shetty

Bangalore

starstarstarstarstar

My doctor included EGFR Mutation Study (10 Common Mutations) as part of an investigation into recurrent health issues with a possible hereditary component. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Ajay Contractor

Bangalore

starstarstarstarstar

My doctor ordered EGFR Mutation Study (10 Common Mutations) after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Venkatesan Rajan

Bangalore

starstarstarstarstar

My oncologist ordered EGFR Mutation Study (10 Common Mutations) for precision medicine planning. I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Lalit Swamy

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included EGFR Mutation Study (10 Common Mutations). My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Debashis Agarwal

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including EGFR Mutation Study (10 Common Mutations). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Sourav Pathak

Bangalore

starstarstarstarstar

My haematologist ordered EGFR Mutation Study (10 Common Mutations) to determine the most appropriate treatment protocol. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Paresh Mishra

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended EGFR Mutation Study (10 Common Mutations) for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Nalini Venkat

Bangalore

starstarstarstarstar

Prenatal genetic screening included EGFR Mutation Study (10 Common Mutations) on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Janki Tripathi

Bangalore

starstarstarstarstar

Pre-conception genetic screening included EGFR Mutation Study (10 Common Mutations) on our genetic counsellor's advice. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Durga Jain

Bangalore

starstarstarstarstar

My doctor ordered EGFR Mutation Study (10 Common Mutations) as part of a genetic investigation. I booked GetVisit in Yelahanka, Bengaluru and the home collection was smooth. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Yuvraj Shetty

Bangalore

starstarstarstarstar

My doctor included EGFR Mutation Study (10 Common Mutations) as part of an investigation into recurrent health issues with a possible hereditary component. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Ajay Contractor

Bangalore

starstarstarstarstar

My doctor ordered EGFR Mutation Study (10 Common Mutations) after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Venkatesan Rajan

Bangalore

starstarstarstarstar

My oncologist ordered EGFR Mutation Study (10 Common Mutations) for precision medicine planning. I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Lalit Swamy

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included EGFR Mutation Study (10 Common Mutations). My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Debashis Agarwal

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including EGFR Mutation Study (10 Common Mutations). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Sourav Pathak

Bangalore