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Centromere IgG Antibody

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Centromere IgG Antibody
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Centromere IgG Antibody, in Bangalore

Detects antibodies against centromere proteins to help diagnose certain autoimmune diseases, mainly limited scleroderma (CREST).

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
24 hours
TEST INCLUDED
1
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20K+Customers
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CertifiedLabs
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4.5+Rating
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What is a Centromere IgG Antibody Test in Bangalore ?

The Centromere IgG Antibody test detects IgG autoantibodies that target centromere proteins inside cell nuclei. These antibodies show that the immune system is reacting against parts of your own cells. They are important because they are strongly associated with limited cutaneous systemic sclerosis (CREST). The test helps detect or support a diagnosis of scleroderma and related autoimmune conditions. Doctors use it together with symptoms, physical exams, and other blood or imaging tests. A positive result can guide monitoring for lung involvement or pulmonary hypertension. A negative result does not fully rule out autoimmune disease, so doctors interpret it in the bigger clinical picture.

Centromere IgG Antibody Test Preparation in Bangalore

No special preparation is required.

Centromere IgG Antibody Test Parameters in Bangalore

The Centromere IgG Antibody test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a Centromere IgG Antibody Test in Bangalore ?

Centromere IgG Antibody is often included in autoimmune antibody panels such as ANA/ENA testing. Doctors may order it when patients have Raynaud’s phenomenon, unexplained skin tightening, reflux, or shortness of breath. It helps diagnose limited systemic sclerosis (CREST) and indicates risk for complications like pulmonary hypertension. Abnormal results are usually caused by autoimmune disease. A family history of scleroderma or other autoimmune disorders may make this test more important.

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Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What is centromere IgG antibody in Bangalore?plus

Centromere IgG antibodies are a subtype of antinuclear antibodies that target centromere proteins (CENP) of chromosomes. Detected by immunofluorescence or ELISA, IgG anticentromere positivity strongly suggests limited cutaneous systemic sclerosis (CREST) and can predict features like pulmonary hypertension and digital ischemia. They are useful diagnostic and prognostic markers in autoimmune connective tissue disease evaluation.

What does it mean when your IgG antibody is positive in Bangalore?plus

A positive IgG antibody test means your immune system has previously encountered the specific pathogen or vaccine and produced IgG antibodies. It usually indicates past infection or immunization and often suggests some degree of immunity, though it doesn’t necessarily rule out current infection or guarantee complete protection. Timing matters—IgG appears later and can persist for months or years depending on the disease.

What diseases are linked to centromere antibodies in Bangalore?plus

Anticentromere antibodies are most strongly linked to systemic sclerosis—especially the limited cutaneous (CREST) form—and to features like Raynaud’s phenomenon and pulmonary hypertension. They can also be present in primary biliary cholangitis and, less commonly, in other autoimmune diseases (eg, Sjögren’s syndrome, systemic lupus erythematosus) or overlap syndromes, where they help indicate disease subset and prognosis.

What causes a positive centromere antibody in Bangalore?plus

A positive anti‑centromere antibody result occurs when the immune system produces antibodies targeting centromere proteins. It is most commonly associated with limited cutaneous systemic sclerosis (CREST syndrome), and can also appear in other autoimmune conditions (e.g., primary biliary cholangitis) or rarely in healthy people. Genetic susceptibility and environmental triggers likely contribute; clinicians use it to support diagnosis and predict features like pulmonary hypertension.

What is the normal range for centromere antibody in Bangalore?plus

Normal (negative) anti‑centromere antibody results depend on method and lab. Common cutoffs: ELISA — <20 U/mL (negative), 20–40 borderline, >40 U/mL (positive); indirect immunofluorescence — titers <1:40 (often <1:80) usually negative, titers ≥1:80 considered significant. Higher titers can indicate limited cutaneous systemic sclerosis or other autoimmune conditions; discuss results with your clinician.

What are the symptoms of scleroderma in Bangalore?plus

Common symptoms of scleroderma include thickening, hardening and tightening of the skin, especially on fingers and face; Raynaud’s phenomenon (cold, numb fingers); swollen, stiff or painful joints; fingertip ulcers and telangiectasias; digestive problems such as reflux and difficulty swallowing; and internal organ involvement causing shortness of breath, cough, or impaired kidney function. Fatigue and reduced hand mobility are also frequent.

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Needed Centromere IgG Antibody for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Shyam Vyas

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. The phlebotomist from GetVisit visited me in HSR Layout, Bengaluru, on time and professional. Centromere IgG Antibody through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Rahul Shetty

Bangalore

starstarstarstarstar

Travel frequently and needed Centromere IgG Antibody before a trip. The GetVisit team in Whitefield, Bengaluru was professional and punctual. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Xavier Bhat

Bangalore

starstarstarstarstar

Pre-travel health check included Centromere IgG Antibody. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Ojas Yadav

Bangalore

starstarstarstarstar

My doctor ordered Centromere IgG Antibody as part of a routine workup. GetVisit, technician arrived on time, professional collection, report within a few hours. My doctor was satisfied with the quality.

Bhushan Kumar

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. Centromere IgG Antibody for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Urvashi Shah

Bangalore

starstarstarstarstar

Comprehensive annual health panel, Centromere IgG Antibody was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Meenakshi Reddy

Bangalore

starstarstarstarstar

Annual workplace health check required Centromere IgG Antibody. I booked GetVisit in JP Nagar, Bengaluru and the home collection was smooth. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Vidya Kapoor

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Centromere IgG Antibody. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Heena Trivedi

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. Centromere IgG Antibody through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Debashis Agarwal

Bangalore

starstarstarstarstar

Needed Centromere IgG Antibody for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Shyam Vyas

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. The phlebotomist from GetVisit visited me in HSR Layout, Bengaluru, on time and professional. Centromere IgG Antibody through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Rahul Shetty

Bangalore

starstarstarstarstar

Travel frequently and needed Centromere IgG Antibody before a trip. The GetVisit team in Whitefield, Bengaluru was professional and punctual. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Xavier Bhat

Bangalore

starstarstarstarstar

Pre-travel health check included Centromere IgG Antibody. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Ojas Yadav

Bangalore

starstarstarstarstar

My doctor ordered Centromere IgG Antibody as part of a routine workup. GetVisit, technician arrived on time, professional collection, report within a few hours. My doctor was satisfied with the quality.

Bhushan Kumar

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. Centromere IgG Antibody for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Urvashi Shah

Bangalore

starstarstarstarstar

Comprehensive annual health panel, Centromere IgG Antibody was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Meenakshi Reddy

Bangalore

starstarstarstarstar

Annual workplace health check required Centromere IgG Antibody. I booked GetVisit in JP Nagar, Bengaluru and the home collection was smooth. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Vidya Kapoor

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Centromere IgG Antibody. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Heena Trivedi

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. Centromere IgG Antibody through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Debashis Agarwal

Bangalore

starstarstarstarstar

Needed Centromere IgG Antibody for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Shyam Vyas

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. The phlebotomist from GetVisit visited me in HSR Layout, Bengaluru, on time and professional. Centromere IgG Antibody through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Rahul Shetty

Bangalore

starstarstarstarstar

Travel frequently and needed Centromere IgG Antibody before a trip. The GetVisit team in Whitefield, Bengaluru was professional and punctual. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Xavier Bhat

Bangalore

starstarstarstarstar

Pre-travel health check included Centromere IgG Antibody. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Ojas Yadav

Bangalore

starstarstarstarstar

My doctor ordered Centromere IgG Antibody as part of a routine workup. GetVisit, technician arrived on time, professional collection, report within a few hours. My doctor was satisfied with the quality.

Bhushan Kumar

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. Centromere IgG Antibody for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Urvashi Shah

Bangalore

starstarstarstarstar

Comprehensive annual health panel, Centromere IgG Antibody was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Meenakshi Reddy

Bangalore

starstarstarstarstar

Annual workplace health check required Centromere IgG Antibody. I booked GetVisit in JP Nagar, Bengaluru and the home collection was smooth. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Vidya Kapoor

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Centromere IgG Antibody. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Heena Trivedi

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. Centromere IgG Antibody through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Debashis Agarwal

Bangalore

starstarstarstarstar

Needed Centromere IgG Antibody for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Shyam Vyas

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. The phlebotomist from GetVisit visited me in HSR Layout, Bengaluru, on time and professional. Centromere IgG Antibody through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Rahul Shetty

Bangalore

starstarstarstarstar

Travel frequently and needed Centromere IgG Antibody before a trip. The GetVisit team in Whitefield, Bengaluru was professional and punctual. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Xavier Bhat

Bangalore

starstarstarstarstar

Pre-travel health check included Centromere IgG Antibody. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Ojas Yadav

Bangalore

starstarstarstarstar

My doctor ordered Centromere IgG Antibody as part of a routine workup. GetVisit, technician arrived on time, professional collection, report within a few hours. My doctor was satisfied with the quality.

Bhushan Kumar

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. Centromere IgG Antibody for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Urvashi Shah

Bangalore

starstarstarstarstar

Comprehensive annual health panel, Centromere IgG Antibody was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Meenakshi Reddy

Bangalore

starstarstarstarstar

Annual workplace health check required Centromere IgG Antibody. I booked GetVisit in JP Nagar, Bengaluru and the home collection was smooth. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Vidya Kapoor

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Centromere IgG Antibody. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Heena Trivedi

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. Centromere IgG Antibody through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Debashis Agarwal

Bangalore