Location
gurugram
Search

CD58 (PNH Marker)

discountup to 50% off
arrow
Tests
arrow
CD58 (PNH Marker)
discountup to 50% off

CD58 (PNH Marker), in Bangalore

Measures CD58 on blood cells to help detect abnormal cell clones and support diagnosis of PNH-related hemolysis.

centreCentre Visit
SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
28 hours
TEST INCLUDED
1
customers
20K+Customers
certified
CertifiedLabs
rating
4.5+Rating
proven
ProvenAccuracy

What is a CD58 (PNH Marker) Test in Bangalore ?

This test measures the amount of CD58 protein on the surface of blood cells. CD58 helps immune cells recognize and talk to each other. Measuring CD58 can reveal abnormal or missing surface proteins on blood cells. Such changes may appear in paroxysmal nocturnal hemoglobinuria (PNH) and related bone marrow disorders. Doctors use CD58 together with other flow cytometry markers to help diagnose PNH, to check how active the disease is, and to monitor response to treatment. The test can be useful when someone has unexplained anemia, dark urine, or unusual blood clots. Results are compared to normal patterns to spot abnormal cell populations.

CD58 (PNH Marker) Test Preparation in Bangalore

No special preparation is required.

CD58 (PNH Marker) Test Parameters in Bangalore

The CD58 (PNH Marker) test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a CD58 (PNH Marker) Test in Bangalore ?

CD58 (PNH Marker) is usually part of a flow cytometry panel used to evaluate suspected PNH or related bone marrow disorders. Doctors may order it when a patient has unexplained anemia, fatigue, dark urine, or blood clots. The test helps detect blood cell clones that lack normal surface proteins. Abnormal results most often reflect an acquired condition such as PNH rather than lifestyle causes. A family history of bone marrow disease or unexplained hemolysis may make testing more important.

How to Book a Test ?

Search & Add Test

Search by test names and add it to your cart

step-image
arrow-right

Select a Lab

Choose your preferred labs from top trusted partners

step-image
arrow-right

Select Date & Slot

Select a convenient date and time for your test

step-image
arrow-right

Pay & Book

Make payment and get confirmation within 2 hours

step-image

Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What are the markers for PNH in Bangalore?plus

PNH markers include flow cytometry demonstrating absent or reduced GPI‑anchored proteins (CD55 and CD59) on red cells and granulocytes. Laboratory evidence of hemolysis—elevated LDH, indirect bilirubin, reticulocytosis, low haptoglobin and hemoglobinuria—is typical. Historical sucrose lysis or Ham (acidified serum) tests may be positive. Patients may also show marrow abnormalities or thrombotic markers (e.g., elevated D‑dimer).

What is CD55 and CD59 in PNH in Bangalore?plus

CD55 (decay‑accelerating factor) and CD59 (protectin) are GPI‑anchored complement regulators on red blood cells. In PNH, PIGA gene–mediated loss of GPI anchors removes CD55 and CD59, allowing unchecked complement activation. CD55 disrupts C3/C5 convertases; CD59 prevents membrane attack complex formation. Their absence causes intravascular hemolysis, hemoglobinuria, anemia and fatigue, with increased thrombosis risk.

What is the gold standard for diagnosing PNH in Bangalore?plus

The gold standard for diagnosing paroxysmal nocturnal hemoglobinuria (PNH) is flow cytometry demonstrating absence or reduced expression of GPI‑anchored proteins (especially CD55 and CD59) on red blood cells and granulocytes. FLAER‑enhanced flow cytometry (using fluorescent aerolysin) provides higher sensitivity and is preferred for detecting PNH clones in granulocytes and monocytes, confirming diagnosis and guiding management.

Is PNH Coombs positive or negative in Bangalore?plus

PNH is typically Coombs-negative. Hemolysis is complement-mediated due to loss of GPI-anchored proteins (CD55/CD59) on red cells, causing intravascular destruction without autoantibodies. Therefore the direct antiglobulin (Coombs) test is usually negative. Rarely, concomitant autoimmune hemolysis can yield a positive Coombs, but classic PNH is diagnosed by flow cytometry showing CD55/CD59 deficiency.

What is the confirmatory test for PNH in Bangalore?plus

The gold-standard confirmatory test for paroxysmal nocturnal hemoglobinuria (PNH) is flow cytometry demonstrating deficiency of GPI-anchored proteins, especially CD55 and CD59, on red cells and myeloid cells. FLAER-based flow cytometry (fluorescent aerolysin) with anti-CD55/CD59 antibodies is the preferred, highly sensitive method; testing granulocytes/monocytes is more reliable than testing transfused red cells.

What is the hallmark of PNH in Bangalore?plus

The hallmark of paroxysmal nocturnal hemoglobinuria (PNH) is complement‑mediated intravascular hemolysis due to loss of GPI‑anchored proteins (notably CD55 and CD59) on red cells. This causes episodic hemoglobinuria (often darker in the morning), hemolytic anemia, and risks of thrombosis and bone marrow failure; diagnosis is by flow cytometry showing absent CD55/CD59 on blood cells.

Visit Health Experience

End-to-end care delivered at the right time through our nationwide network

5,000+

Hospitals/Clinics

Tick India's most trusted health centres
Tick Optional 'You Book, Visit Pays' feature
Tick Cashless coverage from metro to rural
Visit Health Logo
Hospitals/Clinics

65,000+

Doctors & Specialists

Tick Priority access & same-day care
Tick Cashless in 1250+ cities
Tick Custom doctor onboarding
Doctors & Specialists
Doctors & Specialists

7,800+

Diagnostics Partners

Tick NABL-accredited labs
Tick Hassle-free sample collection
Tick Seamless report & prescription tracking
Diagnostics Partners
Diagnostics Partners

19,000+

Pharmacy Delivery Pincodes

Tick Home delivery & store pickup options
Tick End-to-end order tracking
Tick Auto-refills for regular medications
Pharmacy Delivery Pincodes
Pharmacy Delivery Pincodes

Your Care, Our Commitment!

More than 12,000 people trust us with their health

starstarstarstarstar

Travel frequently and needed CD58 (PNH Marker) before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Shruti Sheikh

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included CD58 (PNH Marker). My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Aman Chatterjee

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, CD58 (PNH Marker) was one of several tests she ordered. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Nirmala Aggarwal

Bangalore

starstarstarstarstar

Pre-travel health check included CD58 (PNH Marker). I booked GetVisit in Banashankari, Bengaluru and the home collection was smooth. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Umesh Roy

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including CD58 (PNH Marker). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Pavan More

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. Being in BTM Layout, Bengaluru, home collection services like GetVisit are very useful. CD58 (PNH Marker) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Sonal Bose

Bangalore

starstarstarstarstar

My doctor ordered CD58 (PNH Marker) as part of a routine workup. GetVisit, technician arrived on time, professional collection, report within a few hours. My doctor was satisfied with the quality.

Praveen Das

Bangalore

starstarstarstarstar

Needed CD58 (PNH Marker) for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Sharada Prakash

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. I've been using GetVisit in Whitefield, Bengaluru and would highly recommend it to anyone. CD58 (PNH Marker) through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Bhavna Deshpande

Bangalore

starstarstarstarstar

Hadn't done CD58 (PNH Marker) in two years. GetVisit's home collection removed every excuse, booked the night before, done at 7 am, report on email before noon. All within range. My doctor was relieved to have an updated picture.

Eknath Hegde

Bangalore

starstarstarstarstar

Travel frequently and needed CD58 (PNH Marker) before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Shruti Sheikh

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included CD58 (PNH Marker). My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Aman Chatterjee

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, CD58 (PNH Marker) was one of several tests she ordered. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Nirmala Aggarwal

Bangalore

starstarstarstarstar

Pre-travel health check included CD58 (PNH Marker). I booked GetVisit in Banashankari, Bengaluru and the home collection was smooth. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Umesh Roy

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including CD58 (PNH Marker). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Pavan More

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. Being in BTM Layout, Bengaluru, home collection services like GetVisit are very useful. CD58 (PNH Marker) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Sonal Bose

Bangalore

starstarstarstarstar

My doctor ordered CD58 (PNH Marker) as part of a routine workup. GetVisit, technician arrived on time, professional collection, report within a few hours. My doctor was satisfied with the quality.

Praveen Das

Bangalore

starstarstarstarstar

Needed CD58 (PNH Marker) for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Sharada Prakash

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. I've been using GetVisit in Whitefield, Bengaluru and would highly recommend it to anyone. CD58 (PNH Marker) through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Bhavna Deshpande

Bangalore

starstarstarstarstar

Hadn't done CD58 (PNH Marker) in two years. GetVisit's home collection removed every excuse, booked the night before, done at 7 am, report on email before noon. All within range. My doctor was relieved to have an updated picture.

Eknath Hegde

Bangalore

starstarstarstarstar

Travel frequently and needed CD58 (PNH Marker) before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Shruti Sheikh

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included CD58 (PNH Marker). My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Aman Chatterjee

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, CD58 (PNH Marker) was one of several tests she ordered. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Nirmala Aggarwal

Bangalore

starstarstarstarstar

Pre-travel health check included CD58 (PNH Marker). I booked GetVisit in Banashankari, Bengaluru and the home collection was smooth. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Umesh Roy

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including CD58 (PNH Marker). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Pavan More

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. Being in BTM Layout, Bengaluru, home collection services like GetVisit are very useful. CD58 (PNH Marker) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Sonal Bose

Bangalore

starstarstarstarstar

My doctor ordered CD58 (PNH Marker) as part of a routine workup. GetVisit, technician arrived on time, professional collection, report within a few hours. My doctor was satisfied with the quality.

Praveen Das

Bangalore

starstarstarstarstar

Needed CD58 (PNH Marker) for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Sharada Prakash

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. I've been using GetVisit in Whitefield, Bengaluru and would highly recommend it to anyone. CD58 (PNH Marker) through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Bhavna Deshpande

Bangalore

starstarstarstarstar

Hadn't done CD58 (PNH Marker) in two years. GetVisit's home collection removed every excuse, booked the night before, done at 7 am, report on email before noon. All within range. My doctor was relieved to have an updated picture.

Eknath Hegde

Bangalore

starstarstarstarstar

Travel frequently and needed CD58 (PNH Marker) before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Shruti Sheikh

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included CD58 (PNH Marker). My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Aman Chatterjee

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, CD58 (PNH Marker) was one of several tests she ordered. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Nirmala Aggarwal

Bangalore

starstarstarstarstar

Pre-travel health check included CD58 (PNH Marker). I booked GetVisit in Banashankari, Bengaluru and the home collection was smooth. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Umesh Roy

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including CD58 (PNH Marker). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Pavan More

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. Being in BTM Layout, Bengaluru, home collection services like GetVisit are very useful. CD58 (PNH Marker) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Sonal Bose

Bangalore

starstarstarstarstar

My doctor ordered CD58 (PNH Marker) as part of a routine workup. GetVisit, technician arrived on time, professional collection, report within a few hours. My doctor was satisfied with the quality.

Praveen Das

Bangalore

starstarstarstarstar

Needed CD58 (PNH Marker) for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Sharada Prakash

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. I've been using GetVisit in Whitefield, Bengaluru and would highly recommend it to anyone. CD58 (PNH Marker) through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Bhavna Deshpande

Bangalore

starstarstarstarstar

Hadn't done CD58 (PNH Marker) in two years. GetVisit's home collection removed every excuse, booked the night before, done at 7 am, report on email before noon. All within range. My doctor was relieved to have an updated picture.

Eknath Hegde

Bangalore