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CD55 (PNH Marker), in Bangalore

Measures CD55 on red blood cells to detect PNH and assess risk of complement-related red cell destruction.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
25 hours
TEST INCLUDED
1
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20K+Customers
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CertifiedLabs
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4.5+Rating
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What is a CD55 (PNH Marker) Test in Bangalore ?

The CD55 (PNH Marker) test measures the amount of CD55 protein on red blood cells. CD55 helps protect blood cells from the body's complement system, which can destroy cells if unchecked. Low or absent CD55 is a hallmark of paroxysmal nocturnal hemoglobinuria (PNH). Detecting reduced CD55 helps explain unexplained anemia, dark urine, and unusual blood clots. Doctors use this test with other markers, like CD59, usually by flow cytometry. It helps confirm a PNH diagnosis, estimate the size of the affected cell population, and monitor response to treatments that block complement activity. It can also guide decisions about anticoagulation and specialist care.

CD55 (PNH Marker) Test Preparation in Bangalore

No special preparation is required.

CD55 (PNH Marker) Test Parameters in Bangalore

The CD55 (PNH Marker) test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a CD55 (PNH Marker) Test in Bangalore ?

CD55 (PNH Marker) is usually ordered as part of a hemolysis or PNH flow cytometry panel that also checks CD59 and other markers. Doctors may request it for unexplained anemia, dark or cola-colored urine, or unusual blood clots. It helps diagnose and monitor paroxysmal nocturnal hemoglobinuria and related bone marrow disorders. Abnormal results come from loss of GPI-anchored proteins on blood cells due to acquired mutations and from disease activity; certain blood disorders or treatments can affect results. A family history of unexplained hemolysis or blood disorders may prompt testing.

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Frequently asked questions

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What is CD59 in PNH in Bangalore?plus

CD59 is a GPI‑anchored complement regulatory protein on blood cell membranes that prevents formation of the membrane attack complex (C5b–C9). In PNH, PIGA mutations cause loss of CD59 from red cells and other blood cells, permitting unchecked complement‑mediated intravascular hemolysis and increased thrombosis risk. Flow cytometry detects CD59 deficiency for diagnosis and guides complement‑inhibitor therapy.

What are the markers for PNH in Bangalore?plus

PNH is marked by loss of GPI-anchored proteins—particularly CD55 and CD59—on red cells and leukocytes, detected by flow cytometry (often using FLAER). Laboratory markers include intravascular hemolysis (hemoglobinuria, elevated LDH, low haptoglobin, indirect hyperbilirubinemia, reticulocytosis), cytopenias, and an increased tendency for thrombosis. Historic tests include sucrose lysis or Ham test, but flow cytometry is diagnostic.

What do CD55 and CD59 do in Bangalore?plus

CD55 (decay-accelerating factor) and CD59 (protectin) are membrane proteins that protect host cells from complement-mediated damage. CD55 disrupts formation and accelerates decay of C3/C5 convertases, limiting complement activation. CD59 prevents membrane attack complex formation by blocking C9 polymerization, avoiding cell lysis. Both are broadly expressed on blood cells and endothelium; loss increases complement-driven injury.

What is the gold standard test for PNH in Bangalore?plus

The gold standard test for paroxysmal nocturnal hemoglobinuria (PNH) is flow cytometry demonstrating deficiency of GPI‑anchored proteins on blood cells. Multiparameter flow cytometry uses antibodies to CD55 and CD59 and FLAER (which binds GPI anchors) on red cells, granulocytes, and monocytes to detect and quantify PNH clones with high sensitivity and specificity.

What is the hallmark of PNH in Bangalore?plus

The hallmark of paroxysmal nocturnal hemoglobinuria is complement‑mediated intravascular hemolysis from acquired loss of GPI‑anchored complement regulators (CD55 and CD59) on red cells. This causes episodic hemoglobinuria—often darker in the morning—variable anemia, high thrombosis risk, and potential bone marrow failure. Diagnosis relies on flow cytometry demonstrating loss of these proteins on blood cells.

What is CD59 also called in Bangalore?plus

CD59 is also called protectin or MAC-inhibitory protein (MAC-IP). It is a small GPI‑anchored membrane glycoprotein that protects host cells by preventing formation of the membrane attack complex of complement. Also referred to as the CD59 antigen or CD59 glycoprotein, it helps prevent complement-mediated cell lysis and modulates immune responses.

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Annual workplace health check required CD55 (PNH Marker). Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Tarun Kale

Bangalore

starstarstarstarstar

Needed CD55 (PNH Marker) for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Ramesh Ansari

Bangalore

starstarstarstarstar

My doctor flagged a borderline value at my last check and suggested CD55 (PNH Marker) for further investigation. GetVisit, home collection the next morning, report before my follow-up. My doctor could advise clearly.

Daisy Kale

Bangalore

starstarstarstarstar

Comprehensive annual health panel, CD55 (PNH Marker) was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Nikhil Kapoor

Bangalore

starstarstarstarstar

Travel frequently and needed CD55 (PNH Marker) before a trip. GetVisit's service in Rajajinagar, Bengaluru was excellent, no travel, no waiting rooms. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Ipsita Krishnan

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. The phlebotomist from GetVisit visited me in BTM Layout, Bengaluru, on time and professional. CD55 (PNH Marker) for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Sunil Nair

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. CD55 (PNH Marker) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Jatin Nair

Bangalore

starstarstarstarstar

On a new medication for six months and my doctor wanted to monitor any effects with CD55 (PNH Marker). GetVisit, home collection, same-day report. My doctor assessed the medication's safety profile at my consultation.

Girish Rao

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including CD55 (PNH Marker). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Girija Menon

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, CD55 (PNH Marker) was one of several tests she ordered. GetVisit's service in BTM Layout, Bengaluru was excellent, no travel, no waiting rooms. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Arjun Sharma

Bangalore

starstarstarstarstar

Annual workplace health check required CD55 (PNH Marker). Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Tarun Kale

Bangalore

starstarstarstarstar

Needed CD55 (PNH Marker) for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Ramesh Ansari

Bangalore

starstarstarstarstar

My doctor flagged a borderline value at my last check and suggested CD55 (PNH Marker) for further investigation. GetVisit, home collection the next morning, report before my follow-up. My doctor could advise clearly.

Daisy Kale

Bangalore

starstarstarstarstar

Comprehensive annual health panel, CD55 (PNH Marker) was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Nikhil Kapoor

Bangalore

starstarstarstarstar

Travel frequently and needed CD55 (PNH Marker) before a trip. GetVisit's service in Rajajinagar, Bengaluru was excellent, no travel, no waiting rooms. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Ipsita Krishnan

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. The phlebotomist from GetVisit visited me in BTM Layout, Bengaluru, on time and professional. CD55 (PNH Marker) for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Sunil Nair

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. CD55 (PNH Marker) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Jatin Nair

Bangalore

starstarstarstarstar

On a new medication for six months and my doctor wanted to monitor any effects with CD55 (PNH Marker). GetVisit, home collection, same-day report. My doctor assessed the medication's safety profile at my consultation.

Girish Rao

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including CD55 (PNH Marker). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Girija Menon

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, CD55 (PNH Marker) was one of several tests she ordered. GetVisit's service in BTM Layout, Bengaluru was excellent, no travel, no waiting rooms. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Arjun Sharma

Bangalore

starstarstarstarstar

Annual workplace health check required CD55 (PNH Marker). Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Tarun Kale

Bangalore

starstarstarstarstar

Needed CD55 (PNH Marker) for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Ramesh Ansari

Bangalore

starstarstarstarstar

My doctor flagged a borderline value at my last check and suggested CD55 (PNH Marker) for further investigation. GetVisit, home collection the next morning, report before my follow-up. My doctor could advise clearly.

Daisy Kale

Bangalore

starstarstarstarstar

Comprehensive annual health panel, CD55 (PNH Marker) was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Nikhil Kapoor

Bangalore

starstarstarstarstar

Travel frequently and needed CD55 (PNH Marker) before a trip. GetVisit's service in Rajajinagar, Bengaluru was excellent, no travel, no waiting rooms. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Ipsita Krishnan

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. The phlebotomist from GetVisit visited me in BTM Layout, Bengaluru, on time and professional. CD55 (PNH Marker) for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Sunil Nair

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. CD55 (PNH Marker) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Jatin Nair

Bangalore

starstarstarstarstar

On a new medication for six months and my doctor wanted to monitor any effects with CD55 (PNH Marker). GetVisit, home collection, same-day report. My doctor assessed the medication's safety profile at my consultation.

Girish Rao

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including CD55 (PNH Marker). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Girija Menon

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, CD55 (PNH Marker) was one of several tests she ordered. GetVisit's service in BTM Layout, Bengaluru was excellent, no travel, no waiting rooms. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Arjun Sharma

Bangalore

starstarstarstarstar

Annual workplace health check required CD55 (PNH Marker). Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Tarun Kale

Bangalore

starstarstarstarstar

Needed CD55 (PNH Marker) for an insurance application with a tight deadline. GetVisit, booked in the morning, collected in the afternoon, report the next morning. Accepted by the insurer without any questions.

Ramesh Ansari

Bangalore

starstarstarstarstar

My doctor flagged a borderline value at my last check and suggested CD55 (PNH Marker) for further investigation. GetVisit, home collection the next morning, report before my follow-up. My doctor could advise clearly.

Daisy Kale

Bangalore

starstarstarstarstar

Comprehensive annual health panel, CD55 (PNH Marker) was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Nikhil Kapoor

Bangalore

starstarstarstarstar

Travel frequently and needed CD55 (PNH Marker) before a trip. GetVisit's service in Rajajinagar, Bengaluru was excellent, no travel, no waiting rooms. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Ipsita Krishnan

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. The phlebotomist from GetVisit visited me in BTM Layout, Bengaluru, on time and professional. CD55 (PNH Marker) for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Sunil Nair

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. CD55 (PNH Marker) through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Jatin Nair

Bangalore

starstarstarstarstar

On a new medication for six months and my doctor wanted to monitor any effects with CD55 (PNH Marker). GetVisit, home collection, same-day report. My doctor assessed the medication's safety profile at my consultation.

Girish Rao

Bangalore

starstarstarstarstar

New doctor asked for a baseline set of tests including CD55 (PNH Marker). GetVisit, easy booking, home visit, comprehensive report. My doctor said the lab quality was evidently good and has the results on file.

Girija Menon

Bangalore

starstarstarstarstar

Some general symptoms my doctor wanted to investigate, CD55 (PNH Marker) was one of several tests she ordered. GetVisit's service in BTM Layout, Bengaluru was excellent, no travel, no waiting rooms. All through GetVisit in one home visit. Each report accurate and my doctor could piece together the picture.

Arjun Sharma

Bangalore