Location
gurugram
Search

Beta THALASSEMIA (23 Mutations)

discountup to 50% off
arrow
Tests
arrow
Beta THALASSEMIA (23 Mutations)
discountup to 50% off

Beta THALASSEMIA (23 Mutations), in Bangalore

Detects 23 common beta-globin gene mutations to identify carriers or diagnose beta-thalassemia affecting red blood cells.

homeHome Sample collection
centreCentre Visit
SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
25 hours
TEST INCLUDED
1
customers
20K+Customers
certified
CertifiedLabs
rating
4.5+Rating
proven
ProvenAccuracy

What is a Beta THALASSEMIA (23 Mutations) Test in Bangalore ?

The Beta THALASSEMIA (23 Mutations) test looks for 23 known changes in the HBB gene that affect beta-globin production. Beta-globin is a key part of hemoglobin in red blood cells. Normal hemoglobin carries oxygen throughout the body. Finding these mutations helps identify carriers and people with beta-thalassemia disease. Doctors use results to explain unexplained anemia, plan treatments like transfusions, and offer genetic counseling. The test is often used in preconception and prenatal screening. Results help guide family planning and follow-up care.

Beta THALASSEMIA (23 Mutations) Test Preparation in Bangalore

No special preparation is required.

Beta THALASSEMIA (23 Mutations) Test Parameters in Bangalore

The Beta THALASSEMIA (23 Mutations) test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Panel: DNA analysis for 23 common HBB (beta-globin) gene mutations.

Why Take a Beta THALASSEMIA (23 Mutations) Test in Bangalore ?

Beta THALASSEMIA (23 Mutations) is included in genetic carrier screening and targeted diagnostic panels. Doctors order it for unexplained microcytic anemia, a family history of thalassemia, or during preconception and prenatal checks. It helps diagnose carrier status and disease severity, and it guides treatment planning and genetic counseling. Abnormal results come from inherited HBB gene mutations, so family testing is often recommended.

How to Book a Test ?

Search & Add Test

Search by test names and add it to your cart

step-image
arrow-right

Select a Lab

Choose your preferred labs from top trusted partners

step-image
arrow-right

Select Date & Slot

Select a convenient date and time for your test

step-image
arrow-right

Pay & Book

Make payment and get confirmation within 2 hours

step-image

Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What are the common mutations in beta-thalassemia in Bangalore?plus

Common beta‑thalassemia mutations are HBB gene point changes that disrupt splicing, translation or stability. Frequent examples include IVS‑I‑5 (G→C), IVS‑I‑1 (G→A), IVS‑II‑654 (C→T), codon 41/42 (−CTTT frameshift) and codon 39 (C→T) nonsense. Other pathogenic changes include promoter mutations, small deletions/insertions and occasional large deletions that reduce or abolish β‑globin production.

Which type of mutation is thalassemia in Bangalore?plus

Thalassemia is caused by mutations in the globin genes that reduce or abolish production of alpha or beta hemoglobin chains. These include point mutations, splice‑site and promoter variants, small insertions/deletions and larger gene deletions. Alpha‑thalassemia commonly involves deletions of HBA1/HBA2, while beta‑thalassemia usually involves point or splice‑site mutations in HBB; inheritance is typically autosomal recessive.

Why is it called cooley anemia in Bangalore?plus

"Cooley anemia" is named after American pediatrician Thomas B. Cooley, who in the 1920s first described the severe hereditary form of thalassemia in children. The eponym recognizes his identification of its clinical features—severe anemia, growth failure, and splenomegaly. Today this disorder is usually called beta‑thalassemia major, a genetic defect in hemoglobin production.

What is the cause of the beta-thalassemia mutation in Bangalore?plus

Beta-thalassemia is caused by mutations in the HBB gene on chromosome 11 that reduce or abolish beta‑globin production. Most are single‑base (point) changes, small insertions/deletions, or splicing and promoter defects that impair transcription or mRNA processing. These inherited autosomal recessive mutations produce imbalanced hemoglobin chain synthesis and result in varying severity of anemia.

What is the most common thalassemia mutation in India in Bangalore?plus

The most common thalassemia mutation in India is the beta‑globin gene IVS‑I‑5 (G→C) splice‑site mutation. It is the predominant cause of beta‑thalassemia across many Indian populations, though frequencies vary regionally. Other recurrent mutations include codon 41/42, codon 8/9, and the 619 bp deletion, but IVS‑I‑5 remains the single most frequent defect.

What is a nonsense mutation in Bangalore?plus

A nonsense mutation is a single-base change in DNA that converts a codon for an amino acid into a stop codon. This causes premature termination of protein synthesis, producing a truncated, usually nonfunctional protein. Many nonsense mutations lead to loss of function and can cause genetic diseases; some transcripts are degraded by nonsense-mediated mRNA decay, reducing production of the faulty protein.

Visit Health Experience

End-to-end care delivered at the right time through our nationwide network

5,000+

Hospitals/Clinics

Tick India's most trusted health centres
Tick Optional 'You Book, Visit Pays' feature
Tick Cashless coverage from metro to rural
Visit Health Logo
Hospitals/Clinics

65,000+

Doctors & Specialists

Tick Priority access & same-day care
Tick Cashless in 1250+ cities
Tick Custom doctor onboarding
Doctors & Specialists
Doctors & Specialists

7,800+

Diagnostics Partners

Tick NABL-accredited labs
Tick Hassle-free sample collection
Tick Seamless report & prescription tracking
Diagnostics Partners
Diagnostics Partners

19,000+

Pharmacy Delivery Pincodes

Tick Home delivery & store pickup options
Tick End-to-end order tracking
Tick Auto-refills for regular medications
Pharmacy Delivery Pincodes
Pharmacy Delivery Pincodes

Your Care, Our Commitment!

More than 12,000 people trust us with their health

starstarstarstarstar

My doctor ordered Beta THALASSEMIA (23 Mutations) after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Chetan Verma

Bangalore

starstarstarstarstar

Pre-conception genetic screening included Beta THALASSEMIA (23 Mutations) on our genetic counsellor's advice. I've been using GetVisit in Indiranagar, Bengaluru and would highly recommend it to anyone. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Tejal Solanki

Bangalore

starstarstarstarstar

Prenatal genetic screening included Beta THALASSEMIA (23 Mutations) on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Faisal Venkat

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended Beta THALASSEMIA (23 Mutations) for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Sharmila Datta

Bangalore

starstarstarstarstar

My haematologist ordered Beta THALASSEMIA (23 Mutations) to determine the most appropriate treatment protocol. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Meena Pillai

Bangalore

starstarstarstarstar

My oncologist ordered Beta THALASSEMIA (23 Mutations) for precision medicine planning. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Geeta Murthy

Bangalore

starstarstarstarstar

My doctor ordered Beta THALASSEMIA (23 Mutations) as part of a genetic investigation. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Seema Shukla

Bangalore

starstarstarstarstar

My doctor included Beta THALASSEMIA (23 Mutations) as part of an investigation into recurrent health issues with a possible hereditary component. Being in Yelahanka, Bengaluru, home collection services like GetVisit are very useful. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Janki Tripathi

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. Beta THALASSEMIA (23 Mutations) for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Nilesh Saxena

Bangalore

starstarstarstarstar

Travel frequently and needed Beta THALASSEMIA (23 Mutations) before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Omvati Bhavsar

Bangalore

starstarstarstarstar

My doctor ordered Beta THALASSEMIA (23 Mutations) after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Chetan Verma

Bangalore

starstarstarstarstar

Pre-conception genetic screening included Beta THALASSEMIA (23 Mutations) on our genetic counsellor's advice. I've been using GetVisit in Indiranagar, Bengaluru and would highly recommend it to anyone. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Tejal Solanki

Bangalore

starstarstarstarstar

Prenatal genetic screening included Beta THALASSEMIA (23 Mutations) on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Faisal Venkat

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended Beta THALASSEMIA (23 Mutations) for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Sharmila Datta

Bangalore

starstarstarstarstar

My haematologist ordered Beta THALASSEMIA (23 Mutations) to determine the most appropriate treatment protocol. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Meena Pillai

Bangalore

starstarstarstarstar

My oncologist ordered Beta THALASSEMIA (23 Mutations) for precision medicine planning. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Geeta Murthy

Bangalore

starstarstarstarstar

My doctor ordered Beta THALASSEMIA (23 Mutations) as part of a genetic investigation. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Seema Shukla

Bangalore

starstarstarstarstar

My doctor included Beta THALASSEMIA (23 Mutations) as part of an investigation into recurrent health issues with a possible hereditary component. Being in Yelahanka, Bengaluru, home collection services like GetVisit are very useful. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Janki Tripathi

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. Beta THALASSEMIA (23 Mutations) for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Nilesh Saxena

Bangalore

starstarstarstarstar

Travel frequently and needed Beta THALASSEMIA (23 Mutations) before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Omvati Bhavsar

Bangalore

starstarstarstarstar

My doctor ordered Beta THALASSEMIA (23 Mutations) after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Chetan Verma

Bangalore

starstarstarstarstar

Pre-conception genetic screening included Beta THALASSEMIA (23 Mutations) on our genetic counsellor's advice. I've been using GetVisit in Indiranagar, Bengaluru and would highly recommend it to anyone. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Tejal Solanki

Bangalore

starstarstarstarstar

Prenatal genetic screening included Beta THALASSEMIA (23 Mutations) on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Faisal Venkat

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended Beta THALASSEMIA (23 Mutations) for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Sharmila Datta

Bangalore

starstarstarstarstar

My haematologist ordered Beta THALASSEMIA (23 Mutations) to determine the most appropriate treatment protocol. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Meena Pillai

Bangalore

starstarstarstarstar

My oncologist ordered Beta THALASSEMIA (23 Mutations) for precision medicine planning. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Geeta Murthy

Bangalore

starstarstarstarstar

My doctor ordered Beta THALASSEMIA (23 Mutations) as part of a genetic investigation. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Seema Shukla

Bangalore

starstarstarstarstar

My doctor included Beta THALASSEMIA (23 Mutations) as part of an investigation into recurrent health issues with a possible hereditary component. Being in Yelahanka, Bengaluru, home collection services like GetVisit are very useful. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Janki Tripathi

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. Beta THALASSEMIA (23 Mutations) for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Nilesh Saxena

Bangalore

starstarstarstarstar

Travel frequently and needed Beta THALASSEMIA (23 Mutations) before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Omvati Bhavsar

Bangalore

starstarstarstarstar

My doctor ordered Beta THALASSEMIA (23 Mutations) after a diagnosis that required genetic confirmation for precise management. GetVisit coordinated everything professionally and the report was thorough. My specialist found it exactly what was needed.

Chetan Verma

Bangalore

starstarstarstarstar

Pre-conception genetic screening included Beta THALASSEMIA (23 Mutations) on our genetic counsellor's advice. I've been using GetVisit in Indiranagar, Bengaluru and would highly recommend it to anyone. GetVisit managed the coordination smoothly. The report was detailed and our counsellor could guide our family planning decisions.

Tejal Solanki

Bangalore

starstarstarstarstar

Prenatal genetic screening included Beta THALASSEMIA (23 Mutations) on my specialist's advice. The process was coordinated through GetVisit and handled with care. My ob-gyn found the report thorough and could counsel us based on the results.

Faisal Venkat

Bangalore

starstarstarstarstar

Following a family history assessment, my doctor recommended Beta THALASSEMIA (23 Mutations) for genetic screening. GetVisit managed the referral to a specialist lab. The entire process was professional and the report was comprehensive.

Sharmila Datta

Bangalore

starstarstarstarstar

My haematologist ordered Beta THALASSEMIA (23 Mutations) to determine the most appropriate treatment protocol. GetVisit arranged the specialist collection efficiently. The detailed genetic report helped my doctor personalise my treatment.

Meena Pillai

Bangalore

starstarstarstarstar

My oncologist ordered Beta THALASSEMIA (23 Mutations) for precision medicine planning. The test was coordinated through GetVisit and the genetic lab was excellent, experienced counsellors, thorough report. My oncologist found it very useful.

Geeta Murthy

Bangalore

starstarstarstarstar

My doctor ordered Beta THALASSEMIA (23 Mutations) as part of a genetic investigation. The GetVisit-coordinated lab handled this with great professionalism, the collection was explained clearly, the procedure was well-managed, and the detailed report was ready within the committed timeline.

Seema Shukla

Bangalore

starstarstarstarstar

My doctor included Beta THALASSEMIA (23 Mutations) as part of an investigation into recurrent health issues with a possible hereditary component. Being in Yelahanka, Bengaluru, home collection services like GetVisit are very useful. GetVisit coordinated the collection professionally. The detailed report helped my specialist understand the mechanism.

Janki Tripathi

Bangalore

starstarstarstarstar

Family has been using GetVisit for all health tests for a year. Beta THALASSEMIA (23 Mutations) for me, other tests for family members, professional technicians, reports our doctors consistently find reliable.

Nilesh Saxena

Bangalore

starstarstarstarstar

Travel frequently and needed Beta THALASSEMIA (23 Mutations) before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Omvati Bhavsar

Bangalore