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Aquaporin - 4, in Bangalore

Measures antibodies against aquaporin-4 to help diagnose neuromyelitis optica and guide treatment decisions.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
24 hours
TEST INCLUDED
1
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20K+Customers
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CertifiedLabs
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What is a Aquaporin - 4 Test in Bangalore ?

The Aquaporin-4 test measures antibodies in the blood that target the aquaporin-4 protein. Aquaporin-4 is a water channel found on cells in the central nervous system. It helps control water balance around the brain, spinal cord, and optic nerves. When the immune system makes antibodies against it, those cells can become damaged. This is linked to neuromyelitis optica spectrum disorder (NMOSD). Doctors use the test to help distinguish NMOSD from other nerve conditions and to confirm diagnosis after episodes like optic neuritis or transverse myelitis. Results help guide treatment choices and monitoring over time. Testing is done with a blood sample.

Aquaporin - 4 Test Preparation in Bangalore

No special preparation is required.

Aquaporin - 4 Test Parameters in Bangalore

The Aquaporin - 4 test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a Aquaporin - 4 Test in Bangalore ?

Aquaporin - 4 is usually part of a neurology autoimmune antibody panel when doctors suspect neuromyelitis optica spectrum disorder. Physicians may order it for patients with repeated optic neuritis, sudden vision loss, transverse myelitis, or unexplained spinal cord symptoms and relapses. A positive result supports NMOSD diagnosis and helps guide immunotherapy decisions. Abnormal results reflect autoimmune production of AQP4 antibodies, and prior immunosuppressant use or a family history of autoimmune disease can influence testing and management.

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Frequently asked questions

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What is the function of aquaporin-4 in Bangalore?plus

Aquaporin‑4 is the main water channel in the central nervous system, concentrated in astrocyte endfeet at blood–brain and cerebrospinal fluid interfaces. It facilitates rapid bidirectional water movement to regulate brain water balance, extracellular volume, and cerebrospinal fluid flow, supports potassium buffering and glymphatic clearance of metabolites, and plays a key role in conditions like cerebral edema and autoimmune neuromyelitis optica.

What is the disease associated with aquaporin-4 in Bangalore?plus

Aquaporin‑4 is the target antigen in neuromyelitis optica spectrum disorder (NMOSD), an autoimmune inflammatory demyelinating disease of the central nervous system. Pathogenic AQP4‑IgG antibodies attack astrocyte water channels, causing optic neuritis, longitudinally extensive transverse myelitis, and other brainstem or cerebral symptoms. Detection of AQP4 antibodies is highly specific for NMOSD and guides diagnosis and immunotherapy.

What does aquaporin-4 positive mean in Bangalore?plus

Aquaporin-4 (AQP4) positive means a person has antibodies against the AQP4 water‑channel protein, usually detected in blood or cerebrospinal fluid. This autoantibody signals an autoimmune attack on astrocytes and strongly supports a diagnosis of neuromyelitis optica spectrum disorder (NMOSD). AQP4 positivity helps distinguish NMOSD from multiple sclerosis and guides immunosuppressive treatment and prognosis.

Where are aquaporin-4 channels found in Bangalore?plus

Aquaporin‑4 (AQP4) is a water channel highly concentrated in the central nervous system, especially in astrocyte endfeet at the blood–brain barrier, perivascular and subpial regions, and ependymal surfaces lining ventricles. It’s also present in the retina (Müller cells), optic nerve and spinal cord. Smaller amounts appear in some peripheral tissues, but its primary role is CNS water homeostasis.

What is the main purpose of aquaporins in Bangalore?plus

Aquaporins are membrane channel proteins whose main purpose is to facilitate rapid, selective water transport across cell membranes, enabling fluid balance and osmotic homeostasis in tissues. They support kidney urine concentration, secretion and absorption in glands, brain water regulation, and cellular volume control. Some aquaglyceroporins also transport small solutes like glycerol, contributing to metabolism and cell signaling.

What is another name for aquaporin-4 antibody in Bangalore?plus

Another name for the aquaporin‑4 antibody is AQP4‑IgG, often called NMO‑IgG (neuromyelitis optica immunoglobulin G). These terms refer to autoantibodies that target the aquaporin‑4 water channel on astrocytes and are strongly associated with neuromyelitis optica spectrum disorder (NMOSD). Detection of AQP4‑IgG in blood or cerebrospinal fluid supports diagnosis and guides treatment decisions.

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Started a new exercise programme and my trainer recommended checking Aquaporin - 4 for a baseline. I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Ashok Rajan

Bangalore

starstarstarstarstar

My doctor flagged a borderline value at my last check and suggested Aquaporin - 4 for further investigation. GetVisit, home collection the next morning, report before my follow-up. My doctor could advise clearly.

Sourav Pathak

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. Aquaporin - 4 through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Lakshmi Menon

Bangalore

starstarstarstarstar

Needed Aquaporin - 4 quickly for a specialist consultation. The GetVisit team in Banashankari, Bengaluru was professional and punctual. GetVisit accommodated a same-day appointment, home collection, report within hours. Walked into my consultation with results in hand.

Ishan Iyengar

Bangalore

starstarstarstarstar

Comprehensive annual health panel, Aquaporin - 4 was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Arun Tripathi

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Aquaporin - 4. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Zara D'Souza

Bangalore

starstarstarstarstar

Annual workplace health check required Aquaporin - 4. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Durga Jain

Bangalore

starstarstarstarstar

Travel frequently and needed Aquaporin - 4 before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Mamta Contractor

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. GetVisit in Hebbal, Bengaluru made the whole process so convenient for me. Aquaporin - 4 through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Kanchan Rastogi

Bangalore

starstarstarstarstar

Pre-travel health check included Aquaporin - 4. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Chetan Verma

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking Aquaporin - 4 for a baseline. I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Ashok Rajan

Bangalore

starstarstarstarstar

My doctor flagged a borderline value at my last check and suggested Aquaporin - 4 for further investigation. GetVisit, home collection the next morning, report before my follow-up. My doctor could advise clearly.

Sourav Pathak

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. Aquaporin - 4 through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Lakshmi Menon

Bangalore

starstarstarstarstar

Needed Aquaporin - 4 quickly for a specialist consultation. The GetVisit team in Banashankari, Bengaluru was professional and punctual. GetVisit accommodated a same-day appointment, home collection, report within hours. Walked into my consultation with results in hand.

Ishan Iyengar

Bangalore

starstarstarstarstar

Comprehensive annual health panel, Aquaporin - 4 was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Arun Tripathi

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Aquaporin - 4. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Zara D'Souza

Bangalore

starstarstarstarstar

Annual workplace health check required Aquaporin - 4. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Durga Jain

Bangalore

starstarstarstarstar

Travel frequently and needed Aquaporin - 4 before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Mamta Contractor

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. GetVisit in Hebbal, Bengaluru made the whole process so convenient for me. Aquaporin - 4 through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Kanchan Rastogi

Bangalore

starstarstarstarstar

Pre-travel health check included Aquaporin - 4. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Chetan Verma

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking Aquaporin - 4 for a baseline. I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Ashok Rajan

Bangalore

starstarstarstarstar

My doctor flagged a borderline value at my last check and suggested Aquaporin - 4 for further investigation. GetVisit, home collection the next morning, report before my follow-up. My doctor could advise clearly.

Sourav Pathak

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. Aquaporin - 4 through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Lakshmi Menon

Bangalore

starstarstarstarstar

Needed Aquaporin - 4 quickly for a specialist consultation. The GetVisit team in Banashankari, Bengaluru was professional and punctual. GetVisit accommodated a same-day appointment, home collection, report within hours. Walked into my consultation with results in hand.

Ishan Iyengar

Bangalore

starstarstarstarstar

Comprehensive annual health panel, Aquaporin - 4 was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Arun Tripathi

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Aquaporin - 4. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Zara D'Souza

Bangalore

starstarstarstarstar

Annual workplace health check required Aquaporin - 4. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Durga Jain

Bangalore

starstarstarstarstar

Travel frequently and needed Aquaporin - 4 before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Mamta Contractor

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. GetVisit in Hebbal, Bengaluru made the whole process so convenient for me. Aquaporin - 4 through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Kanchan Rastogi

Bangalore

starstarstarstarstar

Pre-travel health check included Aquaporin - 4. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Chetan Verma

Bangalore

starstarstarstarstar

Started a new exercise programme and my trainer recommended checking Aquaporin - 4 for a baseline. I've been using GetVisit in Malleshwaram, Bengaluru and would highly recommend it to anyone. GetVisit, home collection early morning, report by 9 am, and my trainer could design a nutrition plan.

Ashok Rajan

Bangalore

starstarstarstarstar

My doctor flagged a borderline value at my last check and suggested Aquaporin - 4 for further investigation. GetVisit, home collection the next morning, report before my follow-up. My doctor could advise clearly.

Sourav Pathak

Bangalore

starstarstarstarstar

Made a commitment to be more proactive about health. Aquaporin - 4 through GetVisit is part of that, no excuses about lab distances, book online, collection at home, report before the day is done.

Lakshmi Menon

Bangalore

starstarstarstarstar

Needed Aquaporin - 4 quickly for a specialist consultation. The GetVisit team in Banashankari, Bengaluru was professional and punctual. GetVisit accommodated a same-day appointment, home collection, report within hours. Walked into my consultation with results in hand.

Ishan Iyengar

Bangalore

starstarstarstarstar

Comprehensive annual health panel, Aquaporin - 4 was part of it. Used GetVisit on a family member's recommendation. Home collection at a convenient time, well-formatted report with values and reference ranges delivered digitally. Much easier than a lab visit.

Arun Tripathi

Bangalore

starstarstarstarstar

Post-illness recovery monitoring included Aquaporin - 4. My doctor wanted to check everything had returned to baseline. GetVisit, home collection, detailed report, and my doctor confirmed a full recovery at my follow-up.

Zara D'Souza

Bangalore

starstarstarstarstar

Annual workplace health check required Aquaporin - 4. Used GetVisit for the first time. Professional from start to finish, punctual technician, smooth collection, digital report. Will continue using GetVisit.

Durga Jain

Bangalore

starstarstarstarstar

Travel frequently and needed Aquaporin - 4 before a trip. GetVisit, short-notice appointment, efficient collection, digital report on my phone. Exactly the flexibility I needed.

Mamta Contractor

Bangalore

starstarstarstarstar

In my fifties and take health monitoring seriously. GetVisit in Hebbal, Bengaluru made the whole process so convenient for me. Aquaporin - 4 through GetVisit is now part of my annual routine. Early morning home collection, reports on time, and my doctor has been consistently satisfied.

Kanchan Rastogi

Bangalore

starstarstarstarstar

Pre-travel health check included Aquaporin - 4. GetVisit, online booking, home collection, digital report in a few hours. Had everything I needed before my trip.

Chetan Verma

Bangalore