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Alpha-1-antitrypsin (AAT)
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Alpha-1-antitrypsin (AAT), in Bangalore

Measures the alpha-1-antitrypsin protein in blood to detect deficiency that can damage lungs and liver.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
24 hours
TEST INCLUDED
1
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20K+Customers
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CertifiedLabs
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4.5+Rating
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What is a Alpha-1-antitrypsin (AAT) Test in Bangalore ?

The alpha-1-antitrypsin (AAT) test measures the AAT protein level in blood. AAT is made by the liver and protects lung tissue from damage by enzymes released during inflammation. It helps prevent premature breakdown of elastic tissue in the airways. Low AAT levels increase the risk of emphysema and COPD. Low levels can also cause liver injury, including cirrhosis and neonatal hepatitis. Doctors use this test when people have early lung disease, unexplained liver problems, or a family history of AAT deficiency. It also helps monitor replacement therapy and guides genetic testing and family screening. Results influence treatment, lifestyle advice, and follow-up plans.

Alpha-1-antitrypsin (AAT) Test Preparation in Bangalore

No special preparation is required.

Alpha-1-antitrypsin (AAT) Test Parameters in Bangalore

The Alpha-1-antitrypsin (AAT) test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a Alpha-1-antitrypsin (AAT) Test in Bangalore ?

Alpha-1-antitrypsin (AAT) is often included in lung or liver evaluation panels and in genetic testing when deficiency is suspected. Doctors order it for early-onset emphysema, unexplained liver enzyme elevations, jaundice in infants, or a family history of AAT deficiency. Low results suggest inherited deficiency; high results can reflect inflammation or acute illness. Smoking, chronic inflammation, and certain liver diseases affect results, and abnormal findings may prompt family screening.

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Frequently asked questions

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What is the function of alpha-1 antitrypsin AAT in Bangalore?plus

Alpha-1 antitrypsin (AAT) is a liver-made serine protease inhibitor that protects tissues—especially lung alveoli—by neutralizing enzymes like neutrophil elastase released during inflammation. It limits tissue damage, regulates inflammation, and helps maintain normal lung structure. AAT deficiency allows unchecked elastase activity, causing emphysema, and can lead to liver disease from misfolded AAT accumulation.

What are the symptoms of AAT in Bangalore?plus

Alpha-1 antitrypsin (AAT) deficiency causes lung and liver symptoms: breathlessness, wheeze, chronic cough, recurrent chest infections, reduced exercise tolerance and early-onset emphysema or COPD. Liver signs include jaundice, fatigue, abdominal swelling, hepatomegaly, elevated liver enzymes, cirrhosis and portal hypertension; newborns may have prolonged neonatal jaundice. Less commonly, panniculitis and vasculitis can occur.

What does AAT do in the lungs in Bangalore?plus

Alpha-1 antitrypsin (AAT) is a protective protein that travels from the liver to the lungs, where it neutralizes neutrophil elastase and other proteases. By inhibiting these enzymes, AAT prevents destruction of alveolar walls and preserves lung elasticity, reducing inflammation and the risk of emphysema and COPD. AAT deficiency permits unchecked protease activity, leading to progressive lung tissue damage.

Is alpha-1 antitrypsin deficiency autosomal dominant in Bangalore?plus

Alpha-1 antitrypsin deficiency is not typically autosomal dominant. It follows a codominant pattern: different SERPINA1 alleles (especially Z and S) produce variable AAT levels. Homozygous PiZZ causes severe deficiency and high disease risk; heterozygotes (e.g., MZ, SZ) have intermediate levels and modestly increased risk, especially with smoking or other lung insults.

How is AAT deficiency treated in Bangalore?plus

Treatment focuses on slowing lung damage and managing complications. Key measures include smoking cessation, vaccinations, avoiding pollutants, bronchodilators/inhaled corticosteroids, pulmonary rehabilitation, oxygen therapy, and antibiotics for infections. Selected patients with emphysema receive regular intravenous augmentation with pooled human alpha‑1 antitrypsin. Liver disease is managed supportively and may require transplant in advanced cases. Genetic counselling and family screening are recommended.

Who should consider getting an AAT test in Bangalore?plus

Consider AAT testing if you have early-onset COPD or emphysema (especially before age 45–50), unexplained liver disease or persistent abnormal liver tests, bronchiectasis, or unexplained panniculitis. Also test if a close family member has known alpha‑1 antitrypsin deficiency, or if you have emphysema with little or no smoking history; results guide treatment and family screening.

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starstarstarstarstar

Comprehensive annual health panel included Alpha-1-antitrypsin (AAT). The GetVisit team in Sarjapur, Bengaluru was professional and punctual. I booked everything through GetVisit in one slot. Single visit, all reports on one day, and my doctor found the entire set thorough and well-presented.

Laxmi Mathur

Bangalore

starstarstarstarstar

First time using GetVisit for Alpha-1-antitrypsin (AAT) and I was genuinely impressed. Professional, timely, and the report was detailed. None of the usual problems I'd expected.

Naveen Malhotra

Bangalore

starstarstarstarstar

Slight yellowing in my eyes prompted my doctor to order Alpha-1-antitrypsin (AAT) urgently. I booked through GetVisit late in the evening and managed a morning slot. The technician was at my door before 8 am, the report was ready by noon, and treatment could start the same day.

Wamika Nair

Bangalore

starstarstarstarstar

My gastroenterologist recommended Alpha-1-antitrypsin (AAT) after I mentioned upper abdominal discomfort. Used GetVisit, easy booking, professional home collection, thorough report. My doctor said the lab quality was evidently good.

Debashis Agarwal

Bangalore

starstarstarstarstar

Post-bariatric surgery monitoring includes periodic Alpha-1-antitrypsin (AAT). The GetVisit team in Nagarbhavi, Bengaluru was professional and punctual. The home collection fits any schedule, the reports are well-formatted, and the values have been reliable every time. I've recommended GetVisit to my surgeon's other patients.

Ujjwal Bhosale

Bangalore

starstarstarstarstar

I was anxious before getting Alpha-1-antitrypsin (AAT) because of what it might reveal. GetVisit made the process stress-free, quick booking, a calm technician, a clear report the same day. Everything was in range.

Gaurav Krishnan

Bangalore

starstarstarstarstar

New doctor asked for Alpha-1-antitrypsin (AAT) to establish a baseline before a new medication. GetVisit handled it the next morning. Technician professional, blood draw quick, report ready before my follow-up.

Aditya Krishnan

Bangalore

starstarstarstarstar

Been using GetVisit for Alpha-1-antitrypsin (AAT) for over a year. Consistency is what I appreciate most, always on time, always within the promised window, and my specialist has never questioned the results.

Pankaj Joshi

Bangalore

starstarstarstarstar

Diagnosed with hepatitis B two years ago, Alpha-1-antitrypsin (AAT) every quarter is routine. GetVisit has made that easy, no queuing, home collection, reports on WhatsApp within hours. My hepatologist has been consistently satisfied.

Ramesh Ansari

Bangalore

starstarstarstarstar

Getting Alpha-1-antitrypsin (AAT) done used to mean a half-day at the lab. GetVisit changed that, booked the night before, technician at home by 7 am, digital report before breakfast. My gastroenterologist found the format clean and the values reliable.

Ashok Rajan

Bangalore

starstarstarstarstar

Comprehensive annual health panel included Alpha-1-antitrypsin (AAT). The GetVisit team in Sarjapur, Bengaluru was professional and punctual. I booked everything through GetVisit in one slot. Single visit, all reports on one day, and my doctor found the entire set thorough and well-presented.

Laxmi Mathur

Bangalore

starstarstarstarstar

First time using GetVisit for Alpha-1-antitrypsin (AAT) and I was genuinely impressed. Professional, timely, and the report was detailed. None of the usual problems I'd expected.

Naveen Malhotra

Bangalore

starstarstarstarstar

Slight yellowing in my eyes prompted my doctor to order Alpha-1-antitrypsin (AAT) urgently. I booked through GetVisit late in the evening and managed a morning slot. The technician was at my door before 8 am, the report was ready by noon, and treatment could start the same day.

Wamika Nair

Bangalore

starstarstarstarstar

My gastroenterologist recommended Alpha-1-antitrypsin (AAT) after I mentioned upper abdominal discomfort. Used GetVisit, easy booking, professional home collection, thorough report. My doctor said the lab quality was evidently good.

Debashis Agarwal

Bangalore

starstarstarstarstar

Post-bariatric surgery monitoring includes periodic Alpha-1-antitrypsin (AAT). The GetVisit team in Nagarbhavi, Bengaluru was professional and punctual. The home collection fits any schedule, the reports are well-formatted, and the values have been reliable every time. I've recommended GetVisit to my surgeon's other patients.

Ujjwal Bhosale

Bangalore

starstarstarstarstar

I was anxious before getting Alpha-1-antitrypsin (AAT) because of what it might reveal. GetVisit made the process stress-free, quick booking, a calm technician, a clear report the same day. Everything was in range.

Gaurav Krishnan

Bangalore

starstarstarstarstar

New doctor asked for Alpha-1-antitrypsin (AAT) to establish a baseline before a new medication. GetVisit handled it the next morning. Technician professional, blood draw quick, report ready before my follow-up.

Aditya Krishnan

Bangalore

starstarstarstarstar

Been using GetVisit for Alpha-1-antitrypsin (AAT) for over a year. Consistency is what I appreciate most, always on time, always within the promised window, and my specialist has never questioned the results.

Pankaj Joshi

Bangalore

starstarstarstarstar

Diagnosed with hepatitis B two years ago, Alpha-1-antitrypsin (AAT) every quarter is routine. GetVisit has made that easy, no queuing, home collection, reports on WhatsApp within hours. My hepatologist has been consistently satisfied.

Ramesh Ansari

Bangalore

starstarstarstarstar

Getting Alpha-1-antitrypsin (AAT) done used to mean a half-day at the lab. GetVisit changed that, booked the night before, technician at home by 7 am, digital report before breakfast. My gastroenterologist found the format clean and the values reliable.

Ashok Rajan

Bangalore

starstarstarstarstar

Comprehensive annual health panel included Alpha-1-antitrypsin (AAT). The GetVisit team in Sarjapur, Bengaluru was professional and punctual. I booked everything through GetVisit in one slot. Single visit, all reports on one day, and my doctor found the entire set thorough and well-presented.

Laxmi Mathur

Bangalore

starstarstarstarstar

First time using GetVisit for Alpha-1-antitrypsin (AAT) and I was genuinely impressed. Professional, timely, and the report was detailed. None of the usual problems I'd expected.

Naveen Malhotra

Bangalore

starstarstarstarstar

Slight yellowing in my eyes prompted my doctor to order Alpha-1-antitrypsin (AAT) urgently. I booked through GetVisit late in the evening and managed a morning slot. The technician was at my door before 8 am, the report was ready by noon, and treatment could start the same day.

Wamika Nair

Bangalore

starstarstarstarstar

My gastroenterologist recommended Alpha-1-antitrypsin (AAT) after I mentioned upper abdominal discomfort. Used GetVisit, easy booking, professional home collection, thorough report. My doctor said the lab quality was evidently good.

Debashis Agarwal

Bangalore

starstarstarstarstar

Post-bariatric surgery monitoring includes periodic Alpha-1-antitrypsin (AAT). The GetVisit team in Nagarbhavi, Bengaluru was professional and punctual. The home collection fits any schedule, the reports are well-formatted, and the values have been reliable every time. I've recommended GetVisit to my surgeon's other patients.

Ujjwal Bhosale

Bangalore

starstarstarstarstar

I was anxious before getting Alpha-1-antitrypsin (AAT) because of what it might reveal. GetVisit made the process stress-free, quick booking, a calm technician, a clear report the same day. Everything was in range.

Gaurav Krishnan

Bangalore

starstarstarstarstar

New doctor asked for Alpha-1-antitrypsin (AAT) to establish a baseline before a new medication. GetVisit handled it the next morning. Technician professional, blood draw quick, report ready before my follow-up.

Aditya Krishnan

Bangalore

starstarstarstarstar

Been using GetVisit for Alpha-1-antitrypsin (AAT) for over a year. Consistency is what I appreciate most, always on time, always within the promised window, and my specialist has never questioned the results.

Pankaj Joshi

Bangalore

starstarstarstarstar

Diagnosed with hepatitis B two years ago, Alpha-1-antitrypsin (AAT) every quarter is routine. GetVisit has made that easy, no queuing, home collection, reports on WhatsApp within hours. My hepatologist has been consistently satisfied.

Ramesh Ansari

Bangalore

starstarstarstarstar

Getting Alpha-1-antitrypsin (AAT) done used to mean a half-day at the lab. GetVisit changed that, booked the night before, technician at home by 7 am, digital report before breakfast. My gastroenterologist found the format clean and the values reliable.

Ashok Rajan

Bangalore

starstarstarstarstar

Comprehensive annual health panel included Alpha-1-antitrypsin (AAT). The GetVisit team in Sarjapur, Bengaluru was professional and punctual. I booked everything through GetVisit in one slot. Single visit, all reports on one day, and my doctor found the entire set thorough and well-presented.

Laxmi Mathur

Bangalore

starstarstarstarstar

First time using GetVisit for Alpha-1-antitrypsin (AAT) and I was genuinely impressed. Professional, timely, and the report was detailed. None of the usual problems I'd expected.

Naveen Malhotra

Bangalore

starstarstarstarstar

Slight yellowing in my eyes prompted my doctor to order Alpha-1-antitrypsin (AAT) urgently. I booked through GetVisit late in the evening and managed a morning slot. The technician was at my door before 8 am, the report was ready by noon, and treatment could start the same day.

Wamika Nair

Bangalore

starstarstarstarstar

My gastroenterologist recommended Alpha-1-antitrypsin (AAT) after I mentioned upper abdominal discomfort. Used GetVisit, easy booking, professional home collection, thorough report. My doctor said the lab quality was evidently good.

Debashis Agarwal

Bangalore

starstarstarstarstar

Post-bariatric surgery monitoring includes periodic Alpha-1-antitrypsin (AAT). The GetVisit team in Nagarbhavi, Bengaluru was professional and punctual. The home collection fits any schedule, the reports are well-formatted, and the values have been reliable every time. I've recommended GetVisit to my surgeon's other patients.

Ujjwal Bhosale

Bangalore

starstarstarstarstar

I was anxious before getting Alpha-1-antitrypsin (AAT) because of what it might reveal. GetVisit made the process stress-free, quick booking, a calm technician, a clear report the same day. Everything was in range.

Gaurav Krishnan

Bangalore

starstarstarstarstar

New doctor asked for Alpha-1-antitrypsin (AAT) to establish a baseline before a new medication. GetVisit handled it the next morning. Technician professional, blood draw quick, report ready before my follow-up.

Aditya Krishnan

Bangalore

starstarstarstarstar

Been using GetVisit for Alpha-1-antitrypsin (AAT) for over a year. Consistency is what I appreciate most, always on time, always within the promised window, and my specialist has never questioned the results.

Pankaj Joshi

Bangalore

starstarstarstarstar

Diagnosed with hepatitis B two years ago, Alpha-1-antitrypsin (AAT) every quarter is routine. GetVisit has made that easy, no queuing, home collection, reports on WhatsApp within hours. My hepatologist has been consistently satisfied.

Ramesh Ansari

Bangalore

starstarstarstarstar

Getting Alpha-1-antitrypsin (AAT) done used to mean a half-day at the lab. GetVisit changed that, booked the night before, technician at home by 7 am, digital report before breakfast. My gastroenterologist found the format clean and the values reliable.

Ashok Rajan

Bangalore