GLS stands for global longitudinal strain, an echocardiographic measure of left ventricular systolic function using speckle‑tracking to quantify myocardial deformation. It’s reported as a negative percentage (normal ≈ -18% to -22%); less negative values indicate worse contraction. GLS detects subtle dysfunction earlier than ejection fraction and is used for monitoring cardiotoxicity, valvular disease, and cardiomyopathies.

Normal global longitudinal strain (GLS) by echocardiography is approximately −18% to −22% (commonly quoted as −20% ±2%). GLS values less negative than about −18% (for example −16%) suggest impaired left ventricular longitudinal systolic function, while more negative values indicate better contractility. Reference ranges can vary by vendor and age, so interpret alongside clinical context and lab-specific cutoffs.

Cost varies by country and facility. In the US, global longitudinal strain (GLS) by echocardiography typically costs roughly $200–1,200 if billed separately, often included with a standard echo. In the UK it’s free on the NHS but about £150–400 privately. In India private centres charge approximately ₹800–5,000. Prices depend on hospital type, reporting, and whether GLS is bundled with the echo.

Global longitudinal strain (GLS) assesses left ventricular systolic function; more negative values indicate better contraction. A "good" GLS is typically around −18% to −22% (commonly ≈−20%). Values less negative than about −18% (for example −16%) suggest impaired function. Interpretation varies with imaging vendor, age, and clinical context, so compare with local reference ranges and prior studies.

Normal left ventricular global longitudinal strain (GLS) for a woman is roughly −18% to −22%, with an average around −20% (more negative values reflect better systolic function). Values less negative than about −16% often indicate significant impairment. GLS interpretation varies by imaging vendor and lab; compare results with local reference ranges and the clinical picture.

Charges vary by country and setting. In India, a 2D echocardiogram typically costs roughly INR 500–3,500 at most centres; in the UK it's provided free on the NHS but private clinics charge about £150–£600. In the United States, out-of-pocket or billed costs generally run roughly $300–$3,000 depending on facility and insurance coverage.