Lab Tests

Pr3 - ANCA ( C-ANCA )

up to 50% off

Pr3 - ANCA ( C-ANCA ), in Visit Clinic

Detects antibodies against proteinase 3 in blood to help diagnose and monitor small-vessel autoimmune vasculitis in Visit Clinic.

Centre Visit

₹

SAMPLE TYPE

Blood

FASTING REQUIRED

GENDER

Male/Female

GET REPORTS IN

24 hours

TEST INCLUDED

20K+Customers

CertifiedLabs

4.5+Rating

ProvenAccuracy

What is a Pr3 - ANCA ( C-ANCA ) Test in Visit Clinic?

The Pr3-ANCA (C-ANCA) test measures antibodies in the blood that target proteinase 3, an enzyme in certain white blood cells. These antibodies form when the immune system mistakenly attacks the body. Detecting them helps identify small-vessel vasculitis, especially granulomatosis with polyangiitis. The test is important because early diagnosis can prevent organ damage to the lungs, kidneys, and other tissues. Doctors use it with symptoms, physical exam findings, imaging, and other lab tests. Results help guide treatment choices and monitor how well therapy is working. A positive result supports a diagnosis but is not definitive, so clinicians interpret it in context. Levels can fall with successful treatment or rise during flares. Some infections and medications can affect results, so doctors review your full history.

Pr3 - ANCA ( C-ANCA ) Test Preparation in Visit Clinic

No special preparation is required.

Pr3 - ANCA ( C-ANCA ) Test Parameters in Visit Clinic

The Pr3 - ANCA ( C-ANCA ) test evaluates various parameters. Here are the main parameters checked:

Single test

Why Take a Pr3 - ANCA ( C-ANCA ) Test in Visit Clinic?

Pr3 - ANCA ( C-ANCA ) is often ordered as part of autoimmune or vasculitis panels when doctors suspect granulomatosis with polyangiitis. Symptoms such as chronic cough, sinus pain, blood in the urine, or unexplained fatigue may prompt testing. Abnormal results can arise from autoimmune vasculitis, some infections, or certain medications. A family history of vasculitis or autoimmune disease may make testing more likely.

How to Book a Test ?

Search & Add Test

Search by test names and add it to your cart

Select a Lab

Choose your preferred labs from top trusted partners

Select Date & Slot

Select a convenient date and time for your test

Pay & Book

Make payment and get confirmation within 2 hours

Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

Is PR3-ANCA the same as C-ANCA in Visit Clinic?

PR3-ANCA and C-ANCA are related but not identical. PR3-ANCA refers to antibodies against proteinase‑3 (the specific antigen); C-ANCA describes a cytoplasmic staining pattern on indirect immunofluorescence. Most C-ANCA results reflect PR3-ANCA, and PR3-ANCA typically produces a C-ANCA pattern, but one term is antigen-specific and the other is a lab staining descriptor.

What does P-ANCA and C-Anca test for in Visit Clinic?

P-ANCA and C-ANCA are blood tests that detect antineutrophil cytoplasmic antibodies (ANCAs). C-ANCA usually targets proteinase‑3 (PR3) and is strongly associated with granulomatosis with polyangiitis. P-ANCA often targets myeloperoxidase (MPO) and is linked to microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis, and some inflammatory or autoimmune conditions. They help diagnose and monitor small‑vessel vasculitis.

What diseases are PR3-ANCA positive in Visit Clinic?

PR3‑ANCA is most strongly associated with granulomatosis with polyangiitis (GPA/Wegener’s). It can also be detected in other ANCA‑associated small‑vessel vasculitides (less commonly in microscopic polyangiitis and eosinophilic granulomatosis with polyangiitis), in some drug‑induced ANCA vasculitides, and occasionally with chronic infections or inflammatory conditions that provoke ANCA formation. Clinical correlation and further testing are required to confirm diagnosis.

What does PR3 mean in Visit Clinic?

PR3 stands for proteinase 3, a neutrophil serine protease stored in azurophilic granules that helps kill microbes and process proteins. It is the main autoantigen for PR3‑ANCA (c‑ANCA), an antibody linked to granulomatosis with polyangiitis. Blood tests for PR3 antibodies aid diagnosis and monitoring of ANCA‑associated vasculitis; elevated levels suggest active disease.

Is Wegener's cANCA or P-ANCA in Visit Clinic?

Wegener’s granulomatosis (granulomatosis with polyangiitis) is typically associated with c‑ANCA, most commonly anti‑proteinase 3 (PR3) antibodies. c‑ANCA/PR3 positivity is seen in about 80–90% of generalized cases, though some patients are ANCA‑negative or show p‑ANCA (anti‑MPO) less commonly. Definitive diagnosis combines serology with biopsy and imaging.

Which vasculitis is cANCA in Visit Clinic?

cANCA (cytoplasmic anti‑neutrophil cytoplasmic antibodies) is characteristically associated with granulomatosis with polyangiitis (GPA, formerly Wegener’s). cANCA typically targets proteinase‑3 (PR3) and strongly supports a GPA diagnosis when present, though it isn’t 100% specific; clinical correlation and further testing (imaging, biopsy) are required. Blood cANCA/PR3 levels can help monitor disease activity and treatment response.

Finished scrolling? Now begin experiencing. Let's connect!

COMPANY

About Us We're Hiring Blog Visit Health TV Contact Us

VISIT CARE

Lab & Centers

LEGAL