Lab Tests

Pan B - Cell Marker : CD 22

up to 50% off

Pan B - Cell Marker : CD 22, in Visit Clinic

Measures CD22 protein on B lymphocytes to help diagnose, classify, and monitor B-cell disorders and cancers in Visit Clinic.

Centre Visit

₹

SAMPLE TYPE

Blood

FASTING REQUIRED

GENDER

Male/Female

GET REPORTS IN

26 hours

TEST INCLUDED

20K+Customers

CertifiedLabs

4.5+Rating

ProvenAccuracy

What is a Pan B - Cell Marker : CD 22 Test in Visit Clinic?

The Pan B - Cell Marker CD22 test measures the CD22 protein on the surface of B lymphocytes. CD22 plays a role in how B cells grow, signal, and interact with other immune cells. Measuring CD22 helps show whether B cells are normal or abnormal in number and behavior. This information is useful for diagnosing and classifying B-cell leukemias and lymphomas. The test also helps monitor treatment response and find small amounts of residual disease after therapy. Doctors use it with other tests and clinical findings to guide diagnosis, staging, and targeted treatment choices.

Pan B - Cell Marker : CD 22 Test Preparation in Visit Clinic

No special preparation is required.

Pan B - Cell Marker : CD 22 Test Parameters in Visit Clinic

The Pan B - Cell Marker : CD 22 test evaluates various parameters. Here are the main parameters checked:

Single test

Why Take a Pan B - Cell Marker : CD 22 Test in Visit Clinic?

Pan B - Cell Marker : CD 22 is commonly part of a B-cell immunophenotyping panel used with flow cytometry. Doctors may order it for unexplained swollen lymph nodes, abnormal blood counts, or symptoms suggesting lymphoma or leukemia. It helps diagnose and classify B-cell cancers, monitor treatment response, and detect residual disease. Abnormal results may arise from malignant B-cell growth, infections, autoimmune conditions, or some medications, and family history of blood cancers can raise the need for testing.

How to Book a Test ?

Search & Add Test

Search by test names and add it to your cart

Select a Lab

Choose your preferred labs from top trusted partners

Select Date & Slot

Select a convenient date and time for your test

Pay & Book

Make payment and get confirmation within 2 hours

Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What is CD22 a marker for in Visit Clinic?

CD22 (Siglec‑2) is a B‑cell–restricted transmembrane glycoprotein that helps regulate B‑cell receptor signaling and is used as a marker of the B‑cell lineage. It’s expressed on mature and late‑stage developing B cells (late pre‑B through memory B cells) but is typically absent on plasma cells. CD22 is used in immunophenotyping and as a diagnostic/therapeutic target in B‑cell leukemias and lymphomas.

What are the markers for Pan B cells in Visit Clinic?

Pan-B cell markers include CD19, CD20, CD22, CD79a and CD79b, and the B-lineage transcription factor PAX5. Surface immunoglobulins (sIgM/sIgD) and light chains (kappa/lambda) indicate B-cell receptor expression and clonality. CD45 is commonly used in flow panels to gate leukocytes. These markers identify B-lineage cells across maturation stages in both flow cytometry and immunohistochemistry.

Is CD20 a pan-B-cell marker in Visit Clinic?

CD20 is expressed on most B‑cell stages—from late pre‑B cells through mature and memory B cells—but it is not a true pan‑B‑cell marker. It is absent on early pro‑B cells, hematopoietic stem cells and terminally differentiated plasma cells (and many plasmablasts). Because CD20 is lacking on plasma cells, therapies targeting CD20 do not directly deplete antibody‑secreting plasma cells.

What are the CD B-cell markers in Visit Clinic?

Common B‑cell CD markers include CD19 and CD20 (pan‑B markers), CD21 (CR2) and CD23 (follicular/maturation), CD22 and CD24, CD27 (memory), CD10 (immature/germinal‑center), CD38 and CD138 (activation/plasma cells), and CD79a/CD79b (B‑cell receptor components). Marker expression varies by developmental stage and activation state. These markers guide flow cytometry and immunophenotyping for B‑cell disorders.

Which B cells express CD22 in Visit Clinic?

CD22 (Siglec‑2) is a B‑cell–restricted surface protein expressed broadly on mature B‑lineage cells, including transitional, naïve, memory and germinal‑center B cells in peripheral blood and lymphoid tissues. Expression is low or absent on very early B‑cell precursors (pro‑B stage) and is downregulated or lost when B cells terminally differentiate into antibody‑secreting plasma cells.

What is the full form of CD22 in Visit Clinic?

CD22 stands for Cluster of Differentiation 22. It is a cell-surface molecule expressed primarily on mature B cells, functioning as an inhibitory co-receptor that regulates B-cell receptor signaling, limits activation, and helps maintain immune tolerance. CD22 is used as a diagnostic marker in immunophenotyping and a therapeutic target in certain B-cell malignancies and autoimmune conditions.

Finished scrolling? Now begin experiencing. Let's connect!

COMPANY

About Us We're Hiring Blog Visit Health TV Contact Us

VISIT CARE

Lab & Centers

LEGAL