Myelo Monocytic Cell Marker : CD 64

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Myelo Monocytic Cell Marker : CD 64
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Myelo Monocytic Cell Marker : CD 64, in Visit Clinic

Measures CD64 protein levels on white blood cells to help detect and monitor bacterial infection and sepsis in Visit Clinic.

centreCentre Visit
SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
30 hours
TEST INCLUDED
1
Customers
20K+Customers
Labs
CertifiedLabs
Rating
4.5+Rating
Accuracy
ProvenAccuracy

What is a Myelo Monocytic Cell Marker : CD 64 Test in Visit Clinic?

This test measures CD64, a protein found on certain white blood cells like neutrophils and monocytes. CD64 helps these cells bind antibodies and clear bacteria. Levels often rise quickly during bacterial infections and systemic inflammation. Doctors use CD64 to help detect and monitor sepsis and serious bacterial infections. It also helps distinguish bacterial causes from viral or noninfectious inflammation. The test is usually done by flow cytometry on a blood sample. Results can guide decisions about starting or stopping antibiotics and help track response to treatment. Abnormal results may also reflect some blood cancers or immune disorders and are interpreted with other tests and clinical signs.

Myelo Monocytic Cell Marker : CD 64 Test Preparation in Visit Clinic

No special preparation is required.

Myelo Monocytic Cell Marker : CD 64 Test Parameters in Visit Clinic

The Myelo Monocytic Cell Marker : CD 64 test evaluates various parameters. Here are the main parameters checked:

  • Single test

Why Take a Myelo Monocytic Cell Marker : CD 64 Test in Visit Clinic?

Myelo Monocytic Cell Marker : CD 64 is often included in a flow cytometry infection or sepsis panel and is ordered when a patient has fever, suspected bacterial infection, or unexplained changes in blood counts. It helps detect bacterial infection, monitor response to antibiotics, and distinguish infection from sterile inflammation. Levels change with infections, some blood cancers, and certain medications, and family history of blood disorders can make testing more important.

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Frequently asked questions

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What is CD64 a marker for in Visit Clinic?plus

CD64 (FcγRI) is a high‑affinity IgG receptor whose expression increases on neutrophils and monocytes/macrophages during acute bacterial infection and systemic inflammation. Clinically, elevated neutrophil CD64 is a sensitive marker of neutrophil activation and correlates with disease severity; it helps detect and monitor bacterial sepsis, distinguish bacterial from viral infection, and guide antibiotic decisions and treatment response.

Are monocytes CD64 positive in Visit Clinic?plus

Yes. Human monocytes express CD64 (FcγRI), with classical (CD14++CD16−) and intermediate (CD14++CD16+) subsets showing high CD64 expression, while non‑classical (CD14+CD16++) monocytes have lower levels. CD64 binds the Fc portion of IgG and is upregulated during infection and inflammation, making it useful for diagnostic and research purposes.

Which CD markers indicate leukemia in Visit Clinic?plus

Common CD markers used to identify leukemias include: CD19, CD10, CD22, CD20 (B‑cell ALL/CLL); CD5 and CD23 (CLL); CD3, CD7, CD2 (T‑cell ALL); CD13, CD33, CD117, CD15 (myeloid/AML); and CD34 with HLA‑DR (blast/stem‑cell phenotype). Marker combinations, not single CDs, determine subtype and guide diagnosis and treatment.

What are the CD markers for myeloid cells in Visit Clinic?plus

Myeloid cells commonly express CD14 (monocytes/macrophages), CD11b and CD33 (myeloid lineage), CD15 and CD66b (granulocytes), CD16 and CD64 (Fc receptors on neutrophils/monocytes/macrophages), CD13 (myeloid progenitors), HLA-DR (antigen-presenting myeloid cells), and CD68 (macrophage marker). These markers are used in flow cytometry and pathology to identify and classify myeloid populations.

What is another name for CD64 in Visit Clinic?plus

Another name for CD64 is Fc gamma receptor I (FcγRI), the high-affinity Fc receptor for IgG. CD64 is expressed mainly on macrophages, monocytes and activated neutrophils, where it binds the Fc portion of IgG antibodies and mediates functions such as antibody-dependent phagocytosis, antigen presentation and immune activation.

Is neutrophil CD64 a diagnostic marker for infection and sepsis in Visit Clinic?plus

Neutrophil CD64 is a sensitive and specific biomarker for bacterial infection and sepsis: expression rises rapidly on neutrophils during bacterial inflammation and often correlates with severity. It can aid early diagnosis, guide antibiotic decisions, and monitor response to therapy. Limitations include requirement for flow cytometry, variable cutoff values, and possible false signals in certain inflammatory or hematologic conditions, so it complements clinical assessment.