Lab Tests

HLA CELIAC DISEASE (DQB1*02, 1*03, DQA1*05;01)

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HLA CELIAC DISEASE (DQB102, 103, DQA1*05;01), in Visit Clinic

Checks for HLA genes (DQ2/DQ8) that raise risk of celiac disease and guide diagnosis and management in Visit Clinic.

Centre Visit

₹

SAMPLE TYPE

Blood

FASTING REQUIRED

GENDER

Male/Female

GET REPORTS IN

24 hours

TEST INCLUDED

20K+Customers

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What is a HLA CELIAC DISEASE (DQB1*02, 1*03, DQA1*05;01) Test in Visit Clinic?

This blood test checks for specific HLA gene variants linked with celiac disease, most commonly HLA‑DQ2 and HLA‑DQ8 (for example DQA1*05:01 and DQB1*02). HLA molecules help the immune system tell the body’s own tissues from foreign substances. Having these variants raises the chance of an immune reaction to gluten. Doctors use the test to support or rule out celiac disease when antibody tests or biopsies are unclear. It is also useful for screening relatives and for people who already started a gluten‑free diet. A negative result makes celiac disease very unlikely. A positive result shows genetic risk but does not prove active disease.

HLA CELIAC DISEASE (DQB1*02, 1*03, DQA1*05;01) Test Preparation in Visit Clinic

No special preparation is required.

HLA CELIAC DISEASE (DQB1*02, 1*03, DQA1*05;01) Test Parameters in Visit Clinic

The HLA CELIAC DISEASE (DQB1*02, 1*03, DQA1*05;01) test evaluates various parameters. Here are the main parameters checked:

Single test

Why Take a HLA CELIAC DISEASE (DQB1*02, 1*03, DQA1*05;01) Test in Visit Clinic?

HLA CELIAC DISEASE (DQB1*02, 1*03, DQA1*05;01) is a genetic test often included in a celiac genetics panel and ordered when doctors need to clarify diagnosis. It may be requested for people with chronic abdominal pain, diarrhea, unexplained anemia, or nutrient deficiencies. The test helps identify genetic susceptibility to celiac disease and supports other tests. Results are inherited and not changed by diet, illness, or medication, so family history of celiac disease makes testing more important.

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Frequently asked questions

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What does HLA-DQA1 * 05 positive mean in Visit Clinic?

HLA‑DQA1*05 positive means you carry a specific HLA class II gene variant that influences immune recognition. Carriers are more likely to form anti‑drug antibodies to some biologic therapies (for example anti‑TNF agents), which can lower drug effectiveness and raise risk of reactions. Paired with other HLA alleles it also increases celiac disease risk; clinicians may adjust treatment and monitoring accordingly.

What does HLA-DQA1 * 02 mean in Visit Clinic?

HLA‑DQA1 *02 denotes a specific allele family of the HLA‑DQA1 gene, which encodes the alpha chain of the MHC class II DQ molecule. The *02 label identifies a group of closely related genetic variants (e.g., *02:01) that influence antigen presentation. These inherited variants can affect immune responses, susceptibility to autoimmune diseases, and compatibility for organ or stem‑cell transplantation.

What is DQ2 DQA1 0501 0505 DQB1 02xx in Visit Clinic?

DQ2 DQA1*05:01/*05:05 with DQB1*02:xx denotes HLA‑DQ2 genotypes that form the DQ2 heterodimer. This haplotype is the main genetic predisposition for celiac disease: its presence markedly raises risk but is not diagnostic (many carriers remain healthy). Absence makes celiac unlikely. Results must be interpreted with symptoms and serology/biopsy; genetic testing can aid family screening and diagnostic exclusion.

What is HLA-DQ for celiac disease in Visit Clinic?

HLA-DQ refers to immune-system genes (HLA-DQ2 and HLA-DQ8) that present gluten fragments to T cells and are strongly associated with celiac disease. Nearly all people with celiac carry DQ2 or DQ8, so testing helps rule out disease if both are absent. However, many carriers never develop celiac, so positive results support but do not confirm diagnosis and are used with serology and biopsy.

What is HLA a *02 positive in Visit Clinic?

HLA‑A*02 positive means you carry the HLA‑A*02 variant of the human leukocyte antigen (HLA) class I gene. HLA proteins on cell surfaces help the immune system distinguish self from foreign. Carrying HLA‑A*02 affects transplant compatibility, immune responses to infections and vaccines, and can associate with certain disease risks or drug responses. It is an inherited genetic marker.

What is the risk of HLA celiac disease in Visit Clinic?

HLA‑DQ2 or DQ8 alleles are necessary but not sufficient for celiac disease: about 30–40% of people carry these alleles, yet only roughly 1% develop the disease. Carrying DQ2/DQ8 raises risk, notably in first‑degree relatives (≈10% risk). A negative HLA‑DQ2/DQ8 test makes celiac disease very unlikely, but a positive result alone does not confirm diagnosis.