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Pan T - Cell Marker : CD 2

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Pan T - Cell Marker : CD 2
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Pan T - Cell Marker : CD 2

Measures CD2 on T lymphocytes to assess T-cell levels and help detect immune problems or T-cell cancers.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
27 hours
TEST INCLUDED
1
customers
20K+Customers
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CertifiedLabs
rating
4.5+Rating
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ProvenAccuracy

What is a Pan T - Cell Marker : CD 2 Test ?

The Pan T - Cell Marker CD2 test measures the CD2 protein on the surface of T lymphocytes. CD2 is important for T cell interaction and activation during immune responses. Measuring CD2 helps doctors understand T-cell numbers and types in the body. It is useful for diagnosing and monitoring T-cell leukemias and lymphomas. It also helps evaluate immune deficiency, recovery after transplant, and effects of treatments that change immune cells. The test is usually done by flow cytometry on blood or tissue. Doctors use the results along with other tests and clinical findings to guide diagnosis, therapy choices, and follow-up care for immune and blood disorders.

Pan T - Cell Marker : CD 2 Test Preparation

No special preparation is required.

Pan T - Cell Marker : CD 2 Test Parameters

The Pan T - Cell Marker : CD 2 test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a Pan T - Cell Marker : CD 2 Test ?

Pan T - Cell Marker : CD 2 is commonly ordered as part of a T-cell panel or flow cytometry profile when doctors need to evaluate T-cell numbers and types. It may be requested for unexplained lymphopenia, repeated infections, swollen lymph nodes, abnormal blood counts, or suspected blood cancers. Abnormal results can result from infections, autoimmune disease, chemotherapy, immunosuppressive drugs, or inherited immune disorders. Family history of immunodeficiency or blood cancers can make this test more relevant.

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Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What is the marker CD2 for?plus

CD2 is a surface glycoprotein on T lymphocytes and natural killer cells. It functions as an adhesion and co‑stimulatory molecule, binding LFA‑3 (CD58) to stabilize immune synapses and enhance activation signaling. Clinically, CD2 is used as a pan‑T‑cell/NK‑cell marker in immunophenotyping and flow cytometry to identify and characterize lymphocyte populations and monitor immune disorders.

What is the marker for the pan T cell?plus

CD3 is the pan–T‑cell marker. The CD3 complex is expressed on all mature T lymphocytes and associates with the T‑cell receptor to mediate signal transduction. CD3 detection by flow cytometry or immunohistochemistry identifies total T‑cell populations in clinical and research settings. Other T‑cell markers (CD2, CD5) exist, but CD3 is the standard pan‑T marker.

Is CD2 expressed on T cells?plus

Yes. CD2 is a cell-surface adhesion and signaling molecule expressed on most mature T lymphocytes and on natural killer cells. It binds ligands such as CD58 (LFA‑3) on antigen-presenting cells, enhancing adhesion and promoting T‑cell activation and signaling. CD2 is commonly used as a T‑cell marker in immunophenotyping and aids immune synapse formation and costimulatory interactions.

What does CD2 mean?plus

CD2 (Cluster of Differentiation 2) is a 50–55 kDa transmembrane glycoprotein found mainly on T lymphocytes, thymocytes and natural killer cells. It acts as an adhesion and co‑stimulatory molecule by binding ligands like CD58 (LFA‑3), promoting cell–cell contact and enhancing T‑cell activation and signaling. CD2 is commonly used as a marker in immunophenotyping and immune‑response studies.

What cells are CD2 positive?plus

CD2 is a surface adhesion/co‑stimulatory molecule expressed predominantly on T lymphocytes (including most peripheral T cells and thymocytes) and on natural killer (NK) cells. It is also present on NKT cells and certain activated T‑cell subsets. CD2 is commonly used as a pan‑T cell marker in immunophenotyping and helps mediate T‑cell–antigen presenting cell interactions and activation.

What is CD2 used for?plus

CD2 is a cell-surface protein on T cells and NK cells used mainly as a diagnostic and research marker in immunophenotyping and flow cytometry. It mediates adhesion and co‑stimulatory signaling by binding CD58 (LFA‑3), aiding T‑cell activation and immune synapse formation. Clinically, CD2 helps identify T‑cell populations and assess lymphoproliferative disorders and immune status.

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A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

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