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Enhanced First Trimester Screening

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Enhanced First Trimester Screening
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Enhanced First Trimester Screening

Measures pregnancy blood markers and an ultrasound marker to estimate the baby’s risk for chromosomal conditions.

centreCentre Visit
SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Female
GET REPORTS IN
30 hours
TEST INCLUDED
3
customers
20K+Customers
certified
CertifiedLabs
rating
4.5+Rating
proven
ProvenAccuracy

What is a Enhanced First Trimester Screening Test?

Enhanced first trimester screening measures pregnancy-related substances in your blood and an ultrasound marker. The blood tests commonly check PAPP-A and free beta-hCG. The ultrasound measures fetal nuchal translucency (fluid at the back of the neck). These measurements reflect placental and fetal development. They help estimate the chance of chromosomal conditions like Down syndrome, trisomy 18 and trisomy 13. Doctors use the combined results to give a risk score. That score helps decide if you need more testing. Follow-up may include noninvasive prenatal testing (cell-free DNA) or diagnostic tests like CVS or amniocentesis. The screen is not diagnostic but guides care and counseling.

Enhanced First Trimester Screening Test Preparation

No special preparation is required.

Enhanced First Trimester Screening Test Parameters

The Enhanced First Trimester Screening test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • PAPP-A
  • free beta-hCG blood levels
  • and fetal nuchal translucency ultrasound; sometimes combined with cell-free fetal DNA screening.

Why Take a Enhanced First Trimester Screening Test?

Enhanced First Trimester Screening is usually offered as a combined first-trimester panel of maternal blood markers and an ultrasound measurement. Doctors order it routinely in early pregnancy or sooner if there is advanced maternal age, abnormal ultrasound findings, or a family history of chromosomal conditions. It helps identify pregnancies at higher risk for Down syndrome and other aneuploidies. Abnormal results can come from placental problems, multiple pregnancy, inaccurate dating, maternal weight or smoking, or certain medical conditions and medications. Family history of genetic conditions makes this screening more important.

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Frequently asked questions

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What is the enhanced first trimester screening test?plus

Enhanced first trimester screening combines an ultrasound measurement of nuchal translucency (and sometimes nasal bone) with maternal blood tests for free β‑hCG and PAPP‑A, done at about 10–13+6 weeks. It estimates risk for chromosomal conditions such as Down syndrome and trisomy 18. It’s a non‑diagnostic screen; abnormal results usually lead to offer of cell‑free DNA screening or diagnostic testing (CVS/amniocentesis).

What is the first trimester screening test?plus

The first‑trimester screening test is a combined assessment done at about 11–13+6 weeks’ gestation. It includes an ultrasound measurement of nuchal translucency plus maternal blood tests (PAPP‑A and free beta‑hCG) to estimate the risk of chromosomal conditions such as Down syndrome and trisomy 18. It provides a risk score, not a diagnosis; abnormal results prompt offer of diagnostic testing or cell‑free DNA screening.

When to do enhanced first trimester screening?plus

Enhanced first‑trimester screening (nuchal translucency ultrasound plus maternal serum markers or cell‑free DNA) is performed between 11+0 and 13+6 weeks’ gestation (CRL ≈45–84 mm). It’s offered to all pregnant people, especially those ≥35 or with risk factors. If testing is outside this window, consider second‑trimester screening, cfDNA, or referral for specialist counselling.

Does LifeLabs do enhanced first trimester screening?plus

Yes. LifeLabs offers Enhanced First Trimester Screening (EFTS) where available. EFTS pairs maternal blood tests (PAPP‑A and free β‑hCG) done by the lab with a nuchal translucency ultrasound at an accredited sonography clinic. A physician or midwife requisition is required; results are sent to your clinician. Contact your local LifeLabs or prenatal program for availability and booking.

Is first trimester screening compulsory?plus

First-trimester screening is not compulsory. It’s routinely offered to pregnant people (usually at 11–14 weeks) and involves blood tests and an ultrasound to assess risk for chromosomal conditions. Participation is voluntary—you can accept or decline after counseling. A high‑risk screen result may lead to diagnostic testing, but declining screening does not affect routine prenatal care.

Does NIPT tell gender?plus

NIPT analyzes fetal cell‑free DNA from maternal blood and can usually determine fetal sex with high accuracy (about 95–99%) as early as 10 weeks. It is a screening test, not diagnostic: rare false results can occur due to low fetal fraction, maternal mosaicism, or a vanished twin. Diagnostic tests (CVS/amniocentesis) are used only if definitive confirmation is medically needed.

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Vijay Bisht was friendly, helpful, and made our home test process seamless. Grateful for his timely support and follow-up.

Usha Parvathy

Partner at Deloitte

Deloitte
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A big thank you to Shikhar from the Visit app for going above and beyond to arrange a last-minute appointment during an urgent situation. His seamless coordination truly made a difference.

Tejas Baxix

Associate Vice President

HDFC Life
starstarstarstarstar

A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

Sadaanand Asai

Employee

Deloitte
starstarstarstar

“The service was excellent—she was helpful, efficient, and made my recovery smooth and stress-free. Her support made a real difference.”

Ishan Kaul

Manager Administration

Deloitte
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“Thank you, Shared Gupta, for the great support with my reimbursement claims and Wipro health packages. Truly appreciated!”

Karen Colaco

Employee

Deloitte
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Thank you, Rinku. I appreciate your help during my visit. The hospital staff were courteous and professional. Overall, a very good experience!

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Deloitte
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I want to share my feedback on the help I received for my health checkup. I was happy with the guidance and support. Thank you for your assistance; it made the experience stress-free.

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adityaBirla
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I want to share my feedback on the help I received for my health checkup. I was happy with the guidance and support. Thank you for your assistance; it made the experience stress-free.

Rahul Shelke

Employee

reserveBank
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Huge shoutout to Shikhar from the Visit app! He has been incredibly supportive during emergencies — always responsive and ready to help. Truly impressed by his dedication and calm efficiency.

Somchand

Employee

lic
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“I connected with the concierge team today and spoke with Vijay—he was helpful and made a real effort to address my concerns.”

Archana Bhutani

Employee

McKinsey
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I appreciate Shreshta's outstanding support. She kept me updated on my medicals after hours and ensured everything went smoothly. Her proactive communication and care made a big difference.

Nirmal S

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Wipro
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Wipro
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Hi Aniket, Annu, Mayur, I appreciate Shikhar's support in organizing clinic appointments for my child at odd hours. It's a sensitive matter for any parent, and I'm thankful for his understanding.

Nikhil Sobti

Employee

adityaBirla