Call to Book

Home

Tests

CD42a (Megakaryocytic Cell Marker)

up to 50% off

CD42a (Megakaryocytic Cell Marker)

Measures a platelet surface marker (CD42a) to identify megakaryocytes and detect platelet or bone marrow problems.

Centre Visit

SAMPLE TYPE

Blood

FASTING REQUIRED

GENDER

Male/Female

GET REPORTS IN

25 hours

TEST INCLUDED

20K+Customers

CertifiedLabs

4.5+Rating

ProvenAccuracy

What is a CD42a (Megakaryocytic Cell Marker) Test ?

The CD42a test detects a protein found on platelets and their parent cells, megakaryocytes. This protein helps platelets stick and form clots. Measuring CD42a shows whether cells in blood or bone marrow are from the platelet line. Doctors use it when they need to identify platelet-related cells. It helps find causes of low platelet counts, unexplained bleeding, and some bone marrow disorders. The test is often done with flow cytometry or tissue staining. Results guide diagnosis, treatment planning, and monitoring of conditions that affect platelet production or function. It also helps distinguish platelet problems from other blood cell disorders.

CD42a (Megakaryocytic Cell Marker) Test Preparation

No special preparation is required.

CD42a (Megakaryocytic Cell Marker) Test Parameters

The CD42a (Megakaryocytic Cell Marker) test evaluates various parameters. Here are the main parameters checked:

Single test

Why Take a CD42a (Megakaryocytic Cell Marker) Test ?

CD42a (Megakaryocytic Cell Marker) is often included in platelet or bone marrow immunophenotyping panels and flow cytometry studies. Doctors may order it for unexplained low platelets, abnormal bleeding, bruising, or when bone marrow disease is suspected. It helps diagnose platelet production problems, immune or inherited platelet disorders, and some blood cancers. Abnormal results can come from bone marrow disease, autoimmune destruction, medications, or toxic exposures. A family history of bleeding or inherited platelet disorders can make this test important.

How to Book a Test ?

Search & Add Test

Search by test names and add it to your cart

Select a Lab

Choose your preferred labs from top trusted partners

Select Date & Slot

Select a convenient date and time for your test

Pay & Book

Make payment and get confirmation within 2 hours

Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What are the markers for megakaryocytes?

Megakaryocyte (MK) markers include platelet glycoproteins: CD41 (GPIIb/IIIa), CD61 (GPIIIa), and the CD42 family (GPIb‑IX‑V, e.g., CD42b). They express thrombopoietin receptor MPL (CD110), von Willebrand factor and platelet factor 4, plus lineage markers like CD36. Key transcription factors are GATA‑1, FOG‑1 and NF‑E2. Mature MKs are CD34‑low/negative; they may also express CD9 and GPVI.

What are the CD markers for Megakaryoblast?

Megakaryoblasts typically express platelet-lineage markers CD41 (GPIIb/IIIa) and CD61 (GPIIIa), with CD42 (GPIb complex, e.g., CD42b) appearing as they mature. Early megakaryoblasts often co-express progenitor markers CD34 and CD117 (c‑KIT); CD34 decreases with maturation. CD38 may be positive. They are usually MPO‑negative and show variable CD13/CD33 expression.

What are the CD markers for platelets?

Platelets characteristically express CD41 (integrin αIIb), CD61 (integrin β3), CD42a/b/c (GPIX, GPIbα, GPV), and CD36. They are typically CD45– (non‑leukocyte). Activation markers include CD62P (P‑selectin) and CD63; other associated markers used in flow cytometry are CD9, CD31 (PECAM‑1) and CD47.

What is acute myeloid leukemia with megakaryocytic differentiation?

Acute myeloid leukemia with megakaryocytic differentiation is an AML subtype in which malignant blasts show platelet‑forming (megakaryocytic) features. Diagnosis requires ≥20% blasts with megakaryocyte markers (CD41, CD61) in bone marrow or blood. It can be de novo or secondary to myelodysplasia/therapy, often causes cytopenias, bleeding and organomegaly, and has variable but often poorer prognosis; treatment may include chemotherapy and stem‑cell transplant.

Are megakaryocytes CD45 positive?

Yes. Megakaryocytes are hematopoietic cells that express CD45, though usually at lower intensity than circulating leukocytes (often described as CD45 dim). They characteristically co-express platelet lineage markers (CD41, CD61, CD42) and CD45 levels can vary with maturation and sample preparation — progenitors may show higher CD45 than mature megakaryocytes. Flow cytometry settings affect detection.

What are the bone marrow cell markers?

Bone marrow cell markers include hematopoietic stem cell markers (CD34+ CD38− CD90+ CD45RA−), mesenchymal stromal cell markers (CD73+ CD90+ CD105+; negative for CD34, CD45, CD14, CD19, HLA‑DR), and lineage markers: CD45 (pan‑leukocyte); myeloid CD33/CD13; erythroid CD71/CD235a; B cells CD19/CD20; T cells CD3/CD4/CD8; NK cells CD56/CD16. These markers are used clinically and in research to identify, isolate and characterize bone marrow cell populations.

Visit Health Experience

End-to-end care delivered at the right time through our nationwide network

5,000+

Hospitals/Clinics

India's most trusted health centres

Optional 'You Book, Visit Pays' feature

Cashless coverage from metro to rural

65,000+

Doctors & Specialists

Priority access & same-day care

Cashless in 1250+ cities

Custom doctor onboarding

7,800+

Diagnostics Partners

NABL-accredited labs

Hassle-free sample collection

Seamless report & prescription tracking

19,000+

Pharmacy Delivery Pincodes

Home delivery & store pickup options

End-to-end order tracking

Auto-refills for regular medications

Your Care, Our Commitment!

More than 12,000 people trust us with their health

Vijay Bisht was friendly, helpful, and made our home test process seamless. Grateful for his timely support and follow-up.

Usha Parvathy

Partner at Deloitte

A big thank you to Shikhar from the Visit app for going above and beyond to arrange a last-minute appointment during an urgent situation. His seamless coordination truly made a difference.

Tejas Baxix

Associate Vice President

A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

Sadaanand Asai

Employee

“The service was excellent—she was helpful, efficient, and made my recovery smooth and stress-free. Her support made a real difference.”

Ishan Kaul

Manager Administration

“Thank you, Shared Gupta, for the great support with my reimbursement claims and Wipro health packages. Truly appreciated!”

Karen Colaco

Employee

Thank you, Rinku. I appreciate your help during my visit. The hospital staff were courteous and professional. Overall, a very good experience!

Deepak kumar

Employee

Vijay Bisht was friendly, helpful, and made our home test process seamless. Grateful for his timely support and follow-up.

Usha Parvathy

Partner at Deloitte

A big thank you to Shikhar from the Visit app for going above and beyond to arrange a last-minute appointment during an urgent situation. His seamless coordination truly made a difference.

Tejas Baxix

Associate Vice President

A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

Sadaanand Asai

Employee

“The service was excellent—she was helpful, efficient, and made my recovery smooth and stress-free. Her support made a real difference.”

Ishan Kaul

Manager Administration

“Thank you, Shared Gupta, for the great support with my reimbursement claims and Wipro health packages. Truly appreciated!”

Karen Colaco

Employee

Thank you, Rinku. I appreciate your help during my visit. The hospital staff were courteous and professional. Overall, a very good experience!

Deepak kumar

Employee

I want to share my feedback on the help I received for my health checkup. I was happy with the guidance and support. Thank you for your assistance; it made the experience stress-free.

Rahul Shelke

Employee

Huge shoutout to Shikhar from the Visit app! He has been incredibly supportive during emergencies — always responsive and ready to help. Truly impressed by his dedication and calm efficiency.

Somchand

Employee

“I connected with the concierge team today and spoke with Vijay—he was helpful and made a real effort to address my concerns.”

Archana Bhutani

Employee

I appreciate Shreshta's outstanding support. She kept me updated on my medicals after hours and ensured everything went smoothly. Her proactive communication and care made a big difference.

Nirmal S

Employee

“Grateful to Shikhar for finding a cataract specialist at a convenient time and ensuring a smooth experience. A true asset to the Visit team!”

Shilpa Gupta

Employee

Hi Aniket, Annu, Mayur, I appreciate Shikhar's support in organizing clinic appointments for my child at odd hours. It's a sensitive matter for any parent, and I'm thankful for his understanding.

Nikhil Sobti

Employee

I want to share my feedback on the help I received for my health checkup. I was happy with the guidance and support. Thank you for your assistance; it made the experience stress-free.

Rahul Shelke

Employee

Huge shoutout to Shikhar from the Visit app! He has been incredibly supportive during emergencies — always responsive and ready to help. Truly impressed by his dedication and calm efficiency.

Somchand

Employee

“I connected with the concierge team today and spoke with Vijay—he was helpful and made a real effort to address my concerns.”

Archana Bhutani

Employee

I appreciate Shreshta's outstanding support. She kept me updated on my medicals after hours and ensured everything went smoothly. Her proactive communication and care made a big difference.

Nirmal S

Employee

“Grateful to Shikhar for finding a cataract specialist at a convenient time and ensuring a smooth experience. A true asset to the Visit team!”

Shilpa Gupta

Employee

Hi Aniket, Annu, Mayur, I appreciate Shikhar's support in organizing clinic appointments for my child at odd hours. It's a sensitive matter for any parent, and I'm thankful for his understanding.

Nikhil Sobti

Employee