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CD2 (Pan T Cell Marker)

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CD2 (Pan T Cell Marker)

Measures CD2 on T lymphocytes to assess T‑cell levels and help detect immune disorders and blood cancers.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
24 hours
TEST INCLUDED
1
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20K+Customers
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CertifiedLabs
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4.5+Rating
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ProvenAccuracy

What is a CD2 (Pan T Cell Marker) Test?

The CD2 (Pan T Cell Marker) test measures the CD2 protein on the surface of T lymphocytes. CD2 helps T cells stick to other cells and begin immune responses. Measuring CD2 tells doctors about the number and types of T cells present. It helps detect immune problems, such as primary immunodeficiencies, and blood cancers like T‑cell leukemia or lymphoma. Doctors also use it to monitor recovery after bone marrow transplant and to follow patients on immunosuppressive drugs. Results are usually reported alongside other T‑cell markers to give a complete picture of immune health. The test is done using a blood sample and analyzed by flow cytometry.

CD2 (Pan T Cell Marker) Test Preparation

No special preparation is required.

CD2 (Pan T Cell Marker) Test Parameters

The CD2 (Pan T Cell Marker) test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a CD2 (Pan T Cell Marker) Test?

CD2 (Pan T Cell Marker) is commonly included in lymphocyte subset or flow cytometry panels used to evaluate immune status. Doctors may order it for unexplained infections, persistent low or high lymphocyte counts, or when T‑cell leukemia or lymphoma is suspected. Abnormal results can reflect infections, inherited immune defects, cancers, or effects of medications such as steroids and immunosuppressants. A family history of primary immunodeficiency may prompt earlier or repeated testing.

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Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What is CD2 a marker for?plus

CD2 is a surface glycoprotein used as a marker of T lymphocytes and natural killer (NK) cells. It is present on mature T cells and developing thymocytes, mediating cell adhesion and costimulatory signals during immune activation. Clinically, CD2 is used in immunophenotyping to identify T‑cell lineage and evaluate T‑cell populations in blood, lymphoid tissues, and diagnostic panels.

What is the marker for the pan T cell?plus

CD3 is the pan–T‑cell marker. The CD3 complex is expressed on all mature T lymphocytes as part of the T‑cell receptor (TCR) signaling apparatus and is used in immunophenotyping (flow cytometry, immunohistochemistry) to identify T cells. CD2 and CD5 may also be present on many T cells, but CD3 is the definitive pan‑T marker for diagnostics and research.

Is CD2 expressed on T cells?plus

Yes. CD2 is a surface adhesion and co‑stimulatory glycoprotein expressed broadly on mature T lymphocytes and thymocytes, and also on natural killer (NK) cells. It functions in T‑cell activation and cell–cell adhesion by binding LFA‑3 (CD58) on antigen‑presenting cells, helping immunological synapse formation and signaling in humans and other mammals.

How is CD2 used in immunophenotyping?plus

CD2 is an adhesion and signaling molecule expressed on T lymphocytes and natural killer cells. In immunophenotyping (typically flow cytometry), CD2 helps identify and quantify T/NK-cell populations, assess T-cell lineage in leukemia/lymphoma, evaluate maturation and immunodeficiency, and monitor treatment response. CD2 is included in diagnostic panels to distinguish T-cell from B-cell disorders and detect aberrant antigen expression.

What is CD2 used for?plus

CD2 is a cell-surface protein on T lymphocytes and natural killer cells. It’s used as an immunological marker in flow cytometry and pathology to identify and classify T-cell populations and lymphoid malignancies, and to assess immune function. CD2 also mediates cell adhesion and activation, and is targeted in some research and therapeutic approaches for autoimmune disease and T‑cell leukemias.

What are the CD markers for T cells?plus

T cells are defined primarily by CD3 (pan–T cell complex). Major subsets express CD4 (helper/regulatory) or CD8 (cytotoxic). Other common T‑cell markers include CD2, CD5, CD7 and CD45 (isoforms CD45RA/RO distinguish naïve vs memory). Activation/co‑stimulation markers include CD25, CD69 and CD28; homing/naïve markers include CD62L and CD27.

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