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Ammonia

Measures blood ammonia to assess liver detox function and risk of brain-related symptoms like confusion and sleepiness.

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SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
24 hours
TEST INCLUDED
1
customers
20K+Customers
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CertifiedLabs
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4.5+Rating
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ProvenAccuracy

What is a Ammonia Test?

The ammonia test measures the amount of ammonia in your blood. Ammonia is a waste product made when the body breaks down protein. A healthy liver turns ammonia into urea, which the kidneys remove. High ammonia levels can harm the brain and cause confusion, sleepiness, or coma. Doctors use this test to help find liver failure, hepatic encephalopathy, inherited urea cycle problems, or metabolic imbalance. It helps guide treatment, track recovery, and monitor people with liver disease or unexplained changes in mental state.

Ammonia Test Preparation

Do not eat or drink anything except water for 8-12 hours before the test

Ammonia Test Parameters

The Ammonia test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a Ammonia Test?

Ammonia is often ordered when doctors suspect liver-related brain symptoms or inherited metabolic disorders. It is used alongside liver function tests or metabolic panels. Symptoms such as confusion, drowsiness, vomiting, or sudden mental changes may prompt testing. High or low results can come from liver failure, blocked detox pathways, urea cycle defects, certain medicines, or heavy bleeding in the gut. Family history of metabolic disorders can make this test important.

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Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

Is ammonia NH3 or NH4?plus

Ammonia is the neutral molecule NH3. When it accepts a proton it becomes the positively charged ammonium ion, NH4+. In water an equilibrium exists between NH3 and NH4+; because ammonium’s pKa is about 9.25, at physiological/neutral pH most nitrogen is present as NH4+, while at higher (basic) pH more exists as NH3.

Is ammonia harmful to humans?plus

Yes. Ammonia is a corrosive gas and aqueous solution that can harm humans. Low concentrations irritate eyes, nose, throat and skin; higher or prolonged exposures can cause chemical burns, severe respiratory injury (including pulmonary edema), and even death. Chronic exposure may trigger airway inflammation or asthma-like symptoms. For exposure, move to fresh air, flush affected skin/eyes with water, remove contaminated clothing, and seek medical attention for significant symptoms.

What is ammonia used for?plus

Ammonia is used primarily as a fertilizer feedstock (ammonium compounds), a refrigerant in industrial cooling systems, and a building block for chemicals, plastics, and explosives. It appears in household cleaners, water treatment and pH control, laboratory reagents, and smelling salts/medical stimulants. Industry also uses it for metal treatment and textile production. Its versatility requires careful handling due to toxicity and corrosiveness.

What is ammonia in the human body?plus

Ammonia is a nitrogen-containing waste produced when proteins and amino acids are broken down, and by gut bacteria. The liver converts ammonia into urea via the urea cycle for safe excretion by the kidneys. Excess ammonia is toxic to the brain and can cause confusion, lethargy, or coma, particularly in liver failure or metabolic disorders, so the body tightly regulates its levels.

Why is NH3 toxic to fish?plus

Ammonia (NH3) is toxic because the un‑ionized form diffuses across fish gills, disrupting ionoregulation and acid–base balance, damaging gill tissue and impairing oxygen uptake. It interferes with cellular respiration and neural function, causing metabolic and neurological failure. Toxicity increases with higher pH and temperature, which raise the proportion of NH3 versus the less‑toxic NH4+, leading to rapid stress and mortality.

How is ammonia made?plus

Ammonia is produced industrially by the Haber–Bosch process, combining nitrogen (N2) and hydrogen (H2) over an iron catalyst at ≈400–500°C and 150–300 atm to yield NH3; hydrogen commonly comes from steam‑reformed natural gas or electrolysis. Biologically, ammonia forms during protein and amino‑acid breakdown and via nitrogen‑fixing or decomposing microbes; animals convert excess ammonia to urea for excretion.

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