Location
Gurugram
Search

Precursor Cell Marker : TdT

discountup to 50% off
arrow
Tests
arrow
Precursor Cell Marker : TdT
discountup to 50% off

Precursor Cell Marker : TdT

Measures TdT enzyme in blood or marrow to find immature white blood cells and help diagnose leukemia.

centreCentre Visit
SAMPLE TYPE
Blood
FASTING REQUIRED
No
GENDER
Male/Female
GET REPORTS IN
26 hours
TEST INCLUDED
1
customers
20K+Customers
certified
CertifiedLabs
rating
4.5+Rating
proven
ProvenAccuracy

What is a Precursor Cell Marker : TdT Test?

This test measures the presence of TdT (terminal deoxynucleotyl transferase), an enzyme found in immature white blood cells. TdT is normally present in early precursor lymphoid cells and not in mature blood cells. Detecting TdT helps identify and classify blood cancers that start in immature cells. It is most useful for diagnosing and monitoring acute lymphoblastic leukemia and lymphoblastic lymphoma. Doctors use TdT together with other markers in flow cytometry or tissue staining to confirm a diagnosis, to guide treatment choices, and to track how well treatment is working or if disease returns. Results are interpreted alongside blood counts and other laboratory and clinical findings.

Precursor Cell Marker : TdT Test Preparation

No special preparation is required.

Precursor Cell Marker : TdT Test Parameters

The Precursor Cell Marker : TdT test evaluates various parameters related to the different components. Here are the main parameters that are checked in the test:

  • Single test

Why Take a Precursor Cell Marker : TdT Test?

Precursor Cell Marker : TdT is usually part of a leukemia/lymphoma immunophenotyping panel used in flow cytometry or tissue staining. Doctors order it when blood counts are abnormal or when symptoms like fatigue, infections, bruising, or swollen lymph nodes appear. It helps diagnose and classify acute lymphoblastic leukemia and related conditions. Abnormal results most often reflect malignancy of immature blood cells, and family history of blood cancers may prompt earlier testing.

How to Book a Test ?

Search & Add Test

Search by test names and add it to your cart

step-image
arrow-right

Select a Lab

Choose your preferred labs from top trusted partners

step-image
arrow-right

Select Date & Slot

Select a convenient date and time for your test

step-image
arrow-right

Pay & Book

Make payment and get confirmation within 2 hours

step-image

Frequently asked questions

For any unanswered questions, reach out to our support team via email. We will assist you as soon as possible

What is TdT a marker for?plus

TdT (terminal deoxynucleotidyl transferase) is a nuclear enzyme expressed in immature lymphoid precursors and serves as a marker of lymphoid immaturity. It is routinely used to identify precursor B‑cell and T‑cell acute lymphoblastic leukemia/lymphoma, distinguishing these from mature B‑cell neoplasms. TdT is generally absent in mature lymphocytes and most myeloid leukemias.

Which cells are TdT-positive?plus

TdT is expressed mainly in immature lymphoid cells—precursor B and T lymphoblasts in bone marrow and thymus. It is a nuclear marker of early B‑ and T‑cell development and is typically positive in acute lymphoblastic leukemia/lymphoblastic lymphoma. Mature B cells, plasma cells, and most myeloid and non‑lymphoid cells are TdT‑negative. Occasional rare tumors may show variable TdT expression.

What is the purpose of TdT?plus

Terminal deoxynucleotidyl transferase (TdT) is a specialized DNA polymerase in immature lymphoid cells that inserts non-templated nucleotides at V(D)J junctions during B- and T-cell development, increasing antigen receptor diversity and adaptive immunity. Clinically, TdT expression is used as an immunophenotypic marker of lymphoblasts—especially in acute lymphoblastic leukemia—to aid diagnosis, prognosis, and treatment planning.

What is the full form of TdT?plus

TdT stands for terminal deoxynucleotidyl transferase, a specialized DNA polymerase that adds deoxynucleotides to the 3′ ends of DNA strands without a template. It is predominantly expressed in immature lymphoid cells (precursors in bone marrow and thymus) and is used as an immunohistochemical marker in diagnosing acute lymphoblastic leukemia and lymphoblastic lymphoma.

When is TdT expressed?plus

Terminal deoxynucleotidyl transferase (TdT) is expressed in early lymphoid precursors—pro‑ and pre‑B and pre‑T lymphoblasts in bone marrow and thymus—during V(D)J recombination. It is present in immature lymphocytes but absent in mature B or T cells and plasma cells. TdT is commonly detected in acute lymphoblastic leukemia blasts, reflecting arrested early lymphoid differentiation.

What is TdT disease?plus

TdT (terminal deoxynucleotidyl transferase) is an enzyme marker, not a disease. Its presence in bone marrow or blood cells indicates immature lymphoid cells and is commonly seen in acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma. TdT is detected by immunohistochemistry or flow cytometry; findings are interpreted with cell morphology, immunophenotype, and genetic tests to confirm diagnosis and guide treatment.

Visit Health Experience

End-to-end care delivered at the right time through our nationwide network

5,000+

Hospitals/Clinics

Tick India's most trusted health centres
Tick Optional 'You Book, Visit Pays' feature
Tick Cashless coverage from metro to rural
Visit Health Logo
Hospitals/Clinics

65,000+

Doctors & Specialists

Tick Priority access & same-day care
Tick Cashless in 1250+ cities
Tick Custom doctor onboarding
Doctors & Specialists
Doctors & Specialists

7,800+

Diagnostics Partners

Tick NABL-accredited labs
Tick Hassle-free sample collection
Tick Seamless report & prescription tracking
Diagnostics Partners
Diagnostics Partners

19,000+

Pharmacy Delivery Pincodes

Tick Home delivery & store pickup options
Tick End-to-end order tracking
Tick Auto-refills for regular medications
Pharmacy Delivery Pincodes
Pharmacy Delivery Pincodes

Your Care, Our Commitment!

More than 12,000 people trust us with their health

starstarstarstarstar

Vijay Bisht was friendly, helpful, and made our home test process seamless. Grateful for his timely support and follow-up.

Usha Parvathy

Partner at Deloitte

Deloitte
starstarstarstar

A big thank you to Shikhar from the Visit app for going above and beyond to arrange a last-minute appointment during an urgent situation. His seamless coordination truly made a difference.

Tejas Baxix

Associate Vice President

HDFC Life
starstarstarstarstar

A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

Sadaanand Asai

Employee

Deloitte
starstarstarstar

“The service was excellent—she was helpful, efficient, and made my recovery smooth and stress-free. Her support made a real difference.”

Ishan Kaul

Manager Administration

Deloitte
starstarstarstarstar

“Thank you, Shared Gupta, for the great support with my reimbursement claims and Wipro health packages. Truly appreciated!”

Karen Colaco

Employee

Deloitte
starstarstarstarstar

Thank you, Rinku. I appreciate your help during my visit. The hospital staff were courteous and professional. Overall, a very good experience!

Deepak kumar

Employee

Deloitte
starstarstarstarstar

Vijay Bisht was friendly, helpful, and made our home test process seamless. Grateful for his timely support and follow-up.

Usha Parvathy

Partner at Deloitte

Deloitte
starstarstarstar

A big thank you to Shikhar from the Visit app for going above and beyond to arrange a last-minute appointment during an urgent situation. His seamless coordination truly made a difference.

Tejas Baxix

Associate Vice President

HDFC Life
starstarstarstarstar

A clean facility enhances experience. Quick checkups are a plus. Miss Rinku from Aditya Birla Health Insurance provided excellent service and handled our files well.

Sadaanand Asai

Employee

Deloitte
starstarstarstar

“The service was excellent—she was helpful, efficient, and made my recovery smooth and stress-free. Her support made a real difference.”

Ishan Kaul

Manager Administration

Deloitte
starstarstarstarstar

“Thank you, Shared Gupta, for the great support with my reimbursement claims and Wipro health packages. Truly appreciated!”

Karen Colaco

Employee

Deloitte
starstarstarstarstar

Thank you, Rinku. I appreciate your help during my visit. The hospital staff were courteous and professional. Overall, a very good experience!

Deepak kumar

Employee

Deloitte
starstarstarstarstar

I want to share my feedback on the help I received for my health checkup. I was happy with the guidance and support. Thank you for your assistance; it made the experience stress-free.

Rahul Shelke

Employee

reserveBank
starstarstarstar

Huge shoutout to Shikhar from the Visit app! He has been incredibly supportive during emergencies — always responsive and ready to help. Truly impressed by his dedication and calm efficiency.

Somchand

Employee

lic
starstarstarstar

“I connected with the concierge team today and spoke with Vijay—he was helpful and made a real effort to address my concerns.”

Archana Bhutani

Employee

McKinsey
starstarstarstar

I appreciate Shreshta's outstanding support. She kept me updated on my medicals after hours and ensured everything went smoothly. Her proactive communication and care made a big difference.

Nirmal S

Employee

Wipro
starstarstarstar

“Grateful to Shikhar for finding a cataract specialist at a convenient time and ensuring a smooth experience. A true asset to the Visit team!”

Shilpa Gupta

Employee

Wipro
starstarstarstar

Hi Aniket, Annu, Mayur, I appreciate Shikhar's support in organizing clinic appointments for my child at odd hours. It's a sensitive matter for any parent, and I'm thankful for his understanding.

Nikhil Sobti

Employee

adityaBirla
starstarstarstarstar

I want to share my feedback on the help I received for my health checkup. I was happy with the guidance and support. Thank you for your assistance; it made the experience stress-free.

Rahul Shelke

Employee

reserveBank
starstarstarstar

Huge shoutout to Shikhar from the Visit app! He has been incredibly supportive during emergencies — always responsive and ready to help. Truly impressed by his dedication and calm efficiency.

Somchand

Employee

lic
starstarstarstar

“I connected with the concierge team today and spoke with Vijay—he was helpful and made a real effort to address my concerns.”

Archana Bhutani

Employee

McKinsey
starstarstarstar

I appreciate Shreshta's outstanding support. She kept me updated on my medicals after hours and ensured everything went smoothly. Her proactive communication and care made a big difference.

Nirmal S

Employee

Wipro
starstarstarstar

“Grateful to Shikhar for finding a cataract specialist at a convenient time and ensuring a smooth experience. A true asset to the Visit team!”

Shilpa Gupta

Employee

Wipro
starstarstarstar

Hi Aniket, Annu, Mayur, I appreciate Shikhar's support in organizing clinic appointments for my child at odd hours. It's a sensitive matter for any parent, and I'm thankful for his understanding.

Nikhil Sobti

Employee

adityaBirla